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TRMT11 Knockout Cell Lines

Gene: TRMT11

Official Full Name: tRNA methyltransferase 11 homologprovided by HGNC

Gene Summary: Predicted to enable methyltransferase activity. Predicted to be involved in methylation and tRNA processing. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13014 TRMT11 Knockout cell line (HeLa) Human TRMT11 1:3~1:6 Negative Online Inquiry
KO13015 TRMT11 Knockout cell line (HCT 116) Human TRMT11 1:2~1:4 Negative Online Inquiry
KO13016 TRMT11 Knockout cell line (HEK293) Human TRMT11 1:3~1:6 Negative Online Inquiry
KO13017 TRMT11 Knockout cell line (A549) Human TRMT11 1:3~1:4 Negative Online Inquiry

Background

TRMT11 Gene Knockout Cell Lines are meticulously engineered cell models designed to facilitate the study of the TRMT11 gene's role in cellular processes. TRMT11 encodes a tRNA methyltransferase that is crucial for post-transcriptional modifications of tRNA, a process fundamental to accurate protein synthesis and overall cellular functionality. By creating knockout models for this gene, researchers can effectively investigate the downstream molecular pathways and functional consequences of TRMT11 deficiency, hence gaining insights into conditions related to mitochondrial dysfunction and other metabolic disorders.

The key function of these knockout cell lines lies in their ability to provide a controlled environment for studying gene function. By eliminating TRMT11 expression, researchers can examine the impact on tRNA modification, translation efficiency, and cell viability, enabling detailed analyses of gene-environment interactions. Additionally, these models allow for the assessment of phenotypic changes that may arise from disrupted translational control, opening new avenues for therapeutic interventions.

From a scientific perspective, TRMT11 Gene Knockout Cell Lines are invaluable in both academic research and clinical applications. They serve as vital tools for understanding the molecular basis of diseases linked to tRNA modification, including various cancers and genetic disorders. Their use can accelerate drug discovery efforts by identifying potential therapeutic targets and biomarkers.

What sets our TRMT11 Gene Knockout Cell Lines apart from other available models is not only their precision but also the high-level support provided to researchers in the form of optimized protocols and troubleshooting assistance. As a premier provider of biological products, our company's strong commitment to quality and innovation ensures that customers receive the highest standard of research tools. By incorporating these specialized models into their studies, researchers and clinicians can significantly enhance the accuracy and relevance of their findings, ultimately driving advancements in therapeutic strategies and patient care.

Please note that all services are for research use only. Not intended for any clinical use.

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