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TRMO Knockout Cell Lines

Gene: TRMO

Official Full Name: tRNA methyltransferase Oprovided by HGNC

Gene Summary: Enables tRNA (L-threonylcarbamoyladenosine(37)-C2) methyltransferase activity. Involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22433 TRMO Knockout cell line (HeLa) Human TRMO 1:3~1:6 Negative Online Inquiry
KO22434 TRMO Knockout cell line (HCT 116) Human TRMO 1:2~1:4 Negative Online Inquiry
KO22435 TRMO Knockout cell line (HEK293) Human TRMO 1:3~1:6 Negative Online Inquiry
KO22436 TRMO Knockout cell line (A549) Human TRMO 1:3~1:4 Negative Online Inquiry

Background

TRMO Gene Knockout Cell Lines are a revolutionary tool in molecular biology, designed specifically to facilitate the study of gene function and regulation by effectively silencing target genes through established knockout methodologies. These cell lines are engineered to contain precise genetic alterations that result in the complete absence of specific TRMO genes, thereby allowing researchers to observe the resultant phenotypic changes and molecular pathways influenced by these gene deletions.

The core functionality of TRMO Gene Knockout Cell Lines relies on advanced CRISPR-Cas9 technology, which introduces double-strand breaks in targeted gene sequences. Following this initial modification, the cell’s repair mechanisms fail to accurately repair the break, resulting in the permanent knockout of the gene in question. By harnessing this mechanism, researchers can elucidate the biological roles of TRMO genes in various cellular processes such as proliferation, differentiation, and response to environmental stimuli.

In the scientific arena, these cell lines hold tremendous importance as they provide unparalleled insights into gene function, making them invaluable for both basic research and clinical applications, including drug development and genetic disease modeling. The ability to generate and analyze knockout models accelerates the discovery of therapeutic targets and the validation of disease mechanisms, propelling forward the realms of personalized medicine and biotechnology.

Compared to traditional methods of gene silencing, such as siRNA or shRNA techniques, TRMO Gene Knockout Cell Lines offer distinct advantages. They provide stable, long-term gene disruption, circumventing the transient effects often seen with RNA interference. Moreover, these cell lines ensure precise targeting, minimizing off-target effects, thus improving the reliability and reproducibility of experimental outcomes.

For researchers and clinicians, the value of TRMO Gene Knockout Cell Lines is evident; they serve as a robust platform for investigative studies, enabling superior data generation and accelerating the pathway from research to clinical application. Utilizing these cell lines ensures that experiments yield relevant, high-quality insights that can translate into significant scientific advancements.

At [Your Company Name], we pride ourselves on our expertise in developing cutting-edge biological tools tailored to the needs of the scientific community. Our commitment to excellence in production and customer support ensures that our TRMO Gene Knockout Cell Lines are not only of the highest quality but also readily accessible to advance your research initiatives.

Please note that all services are for research use only. Not intended for any clinical use.

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