Gene: TRIO
Official Full Name: trio Rho guanine nucleotide exchange factorprovided by HGNC
Gene Summary: This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34930 | TRIO Knockout cell line (HeLa) | Human | TRIO | 1:3~1:6 | Negative | Online Inquiry |
KO34931 | TRIO Knockout cell line (HCT 116) | Human | TRIO | 1:2~1:4 | Negative | Online Inquiry |
KO34932 | TRIO Knockout cell line (HEK293) | Human | TRIO | 1:3~1:6 | Negative | Online Inquiry |
KO34933 | TRIO Knockout cell line (A549) | Human | TRIO | 1:3~1:4 | Negative | Online Inquiry |
TRIO Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology designed for the targeted disruption of specific genes within a cellular context. Utilizing advanced CRISPR-Cas9 technology, these cell lines enable researchers to generate gene knockout models efficiently and precisely, facilitating the study of gene function and regulation.
The key function of TRIO Gene Knockout Cell Lines lies in their ability to employ an engineered version of the Cas9 enzyme to create double-strand breaks at specific loci in the genome. This process triggers the cell’s natural repair mechanisms, leading to insertions or deletions (indels) that can result in the functional loss of the gene of interest. Researchers can thus observe the phenotypic and molecular consequences of gene disruption, allowing for deeper insights into various biological processes, disease mechanisms, and therapeutic targets.
The scientific importance of these cell lines is underscored by their applications across a variety of fields, including cancer research, gene therapy, drug development, and biotechnology. By providing a platform to elucidate the roles of specific genes, TRIO Gene Knockout Cell Lines are invaluable for both basic and applied research settings.
What sets TRIO Gene Knockout Cell Lines apart from traditional knockout models is their high efficiency and specificity, reduced time to experimental readiness, and the removal of the labor-intensive procedures often associated with generating knockout cells. This makes them a superior choice for researchers seeking rapid results and reproducibility in their experiments.
For researchers and clinicians, the value of these cell lines lies in their capacity to advance our understanding of complex biological systems, elucidate gene functions, and model diseases more accurately. Such insights can lead to the identification of new biomarkers, therapeutic strategies, and innovative treatments.
Our company brings extensive expertise in genetic engineering and cell line development, ensuring that our TRIO Gene Knockout Cell Lines meet the highest standards of quality and reliability. We are committed to providing researchers with the tools they need to make groundbreaking discoveries in their respective fields.
Please note that all services are for research use only. Not intended for any clinical use.
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