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TRIM75 Knockout Cell Lines

Gene: TRIM75

Official Full Name: tripartite motif containing 75provided by HGNC

Gene Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in female meiosis I and innate immune response. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13042 TRIM75 Knockout cell line (HeLa) Human TRIM75 1:3~1:6 Negative Online Inquiry
KO13043 TRIM75 Knockout cell line (HCT 116) Human TRIM75 1:2~1:4 Negative Online Inquiry
KO13044 TRIM75 Knockout cell line (HEK293) Human TRIM75 1:3~1:6 Negative Online Inquiry
KO13045 TRIM75 Knockout cell line (A549) Human TRIM75 1:3~1:4 Negative Online Inquiry

Background

TRIM75 Gene Knockout Cell Lines are an advanced biological product developed to facilitate the study of gene function and associated pathways through targeted genetic manipulation. These cell lines have been engineered using CRISPR/Cas9 technology to ablate the expression of the TRIM75 gene, a member of the tripartite motif-containing proteins implicated in various cellular processes, including immune response regulation and oncogenesis.

The primary function of the TRIM75 Gene Knockout Cell Lines lies in providing researchers with a precise cellular model that allows for the investigation of the role TRIM75 plays in different biological contexts. By removing the gene's expression, scientists can observe changes in cellular behavior, protein interactions, and metabolic pathways, elucidating the gene's contributions to diseases and potential therapeutic targets. The mechanisms underlying this knockout involve insertion or deletion mutations that prevent the production of functional TRIM75 proteins, thereby allowing for a clearer understanding of its functional dynamics.

The scientific importance of these knockout cell lines extends to various research and clinical applications, including cancer biology, immunotherapy, and targeted drug development. By offering insights into the TRIM75-mediated pathways, these cell lines can aid in the identification of novel drug targets and inform treatment strategies, potentially leading to enhanced patient outcomes.

What sets our TRIM75 Gene Knockout Cell Lines apart from other genetic models is their high specificity and reliability, enabling reproducible results in downstream assays, including pharmacological studies and gene editing validation. Furthermore, they are validated for multiple assays, thus saving time and resources while maximizing experimental efficiency.

Our TRIM75 Gene Knockout Cell Lines serve as an invaluable tool for researchers and clinicians focused on gene regulation and its implications in human health. With extensive experience in developing innovative biological products, our company is committed to providing high-quality research tools that empower our clients to advance their scientific investigations.

Please note that all services are for research use only. Not intended for any clinical use.

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