Gene: TRIM66
Official Full Name: tripartite motif containing 66provided by HGNC
Gene Summary: Predicted to enable chromatin binding activity; identical protein binding activity; and zinc ion binding activity. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32614 | TRIM66 Knockout cell line (HeLa) | Human | TRIM66 | 1:3~1:6 | Negative | Online Inquiry |
KO32615 | TRIM66 Knockout cell line (HCT 116) | Human | TRIM66 | 1:2~1:4 | Negative | Online Inquiry |
KO32616 | TRIM66 Knockout cell line (HEK293) | Human | TRIM66 | 1:3~1:6 | Negative | Online Inquiry |
KO32617 | TRIM66 Knockout cell line (A549) | Human | TRIM66 | 1:3~1:4 | Negative | Online Inquiry |
TRIM66 Gene Knockout Cell Lines are specialized cellular models engineered to facilitate the investigation of the TRIM66 gene's functions in various biological processes. These cell lines have undergone targeted genomic editing to disrupt the TRIM66 gene, allowing researchers to study its role in cellular activities such as proliferation, differentiation, and signal transduction. TRIM66, a member of the tripartite motif (TRIM) family of proteins, is implicated in various cellular functions, including gene regulation, protein degradation, and cellular stress response mechanisms.
The key function of these knockout cell lines lies in their ability to serve as a vital tool for elucidating the therapeutic potential of TRIM66 by providing insights into the consequences of its absence. By utilizing these cell lines in experiments, researchers can assess changes in cellular behavior and gene expression profiles, leading to a deeper understanding of diseases such as cancer, neurodegenerative disorders, and other conditions associated with dysregulated TRIM66 activity.
In the context of scientific research and clinical applications, TRIM66 Gene Knockout Cell Lines are invaluable for translational studies aimed at developing targeted therapies. Their consistent performance and reproducibility make them a robust choice for laboratories focused on gene function analysis and drug discovery. Compared to other models, these knockout cell lines offer a precise and controlled environment to unravel the complexities of TRIM66 function without the confounding effects of gene expression variability present in wild-type cells.
Furthermore, the use of TRIM66 Knockout Cell Lines allows researchers to leverage advanced techniques such as CRISPR-Cas9 technology, enhancing their capability to develop innovative approaches to genetic and epigenetic research. Researchers and clinicians alike will find immense value in these cell lines, as they not only save time and resources but also provide critical insights that can lead to significant breakthroughs in understanding tumorigenesis and treatment response.
With a commitment to advancing scientific research, our company specializes in developing high-quality genetically modified cell lines that support the evolving needs of the research community. Our expertise ensures that you receive reliable and effective tools for your studies, reinforcing our dedication to fostering scientific excellence.
Please note that all services are for research use only. Not intended for any clinical use.
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