Gene: TRIM52
Official Full Name: tripartite motif containing 52provided by HGNC
Gene Summary: Enables transcription coactivator activity and ubiquitin protein ligase activity. Involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of canonical NF-kappaB signal transduction; and protein autoubiquitination. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24591 | TRIM52 Knockout cell line (HeLa) | Human | TRIM52 | 1:3~1:6 | Negative | Online Inquiry |
KO24592 | TRIM52 Knockout cell line (HCT 116) | Human | TRIM52 | 1:2~1:4 | Negative | Online Inquiry |
KO24593 | TRIM52 Knockout cell line (HEK293) | Human | TRIM52 | 1:3~1:6 | Negative | Online Inquiry |
KO24594 | TRIM52 Knockout cell line (A549) | Human | TRIM52 | 1:3~1:4 | Negative | Online Inquiry |
TRIM52 Gene Knockout Cell Lines are a cutting-edge biological tool designed for research into the cellular functions and regulatory roles of the TRIM52 gene. TRIM52, a member of the tripartite motif (TRIM) protein family, is implicated in various cellular processes, including immune response, cell proliferation, and differentiation. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines allow for precise deletion or modification of the TRIM52 gene, providing researchers with a powerful means to study the resultant phenotypic changes and their implications in both normal physiology and disease states.
The key functions of the TRIM52 Gene Knockout Cell Lines lie in their ability to facilitate the dissection of complex cellular pathways and interactions. By observing the biological outcomes following TRIM52 gene knockout, researchers can elucidate the gene’s function in processes such as inflammatory responses and cancer progression. Additionally, these cell lines can serve as critical models for drug discovery and toxicity testing, thus broadening their utility in both basic and applied bioscience.
Scientifically, the importance of TRIM52 Gene Knockout Cell Lines is underscored by their applications in both research and clinical settings. Studies have linked TRIM52 to immunological disorders and various cancers, thereby marking it as a potential therapeutic target. The ability to knock out this gene allows for advanced investigation into its role in pathophysiology, paving the way for innovative treatment strategies. Compared to alternative cell lines that may not offer the same specificity or functionality, TRIM52 Gene Knockout Cell Lines provide an unparalleled level of experimental control and insight.
Moreover, these cell lines come with the significant advantage of being validated and optimized for robust performance, ensuring reliable and reproducible results. Their ease of use and integration into existing research frameworks make them a valuable addition to any laboratory focused on molecular biology, genetics, or translational medicine.
At [Your Company Name], we are committed to advancing scientific inquiry through our specialized expertise in custom cell line development. Our TRIM52 Gene Knockout Cell Lines represent our continued dedication to providing researchers and clinicians with high-quality tools that drive discovery and innovation in biological sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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