Gene: TRIM46
Official Full Name: tripartite motif containing 46provided by HGNC
Gene Summary: This gene encodes a protein of the tripartite motif (TRIM) family. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. TRIM46 is reported to be involved in the proliferation of multiple types of cancer cells including lung and breast cancer. It has also been shown to control neuronal polarity and axon specification by forming uniform microtubule bundles in the axon. [provided by RefSeq, May 2022]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26220 | TRIM46 Knockout cell line (HeLa) | Human | TRIM46 | 1:3~1:6 | Negative | Online Inquiry |
KO26221 | TRIM46 Knockout cell line (HCT 116) | Human | TRIM46 | 1:2~1:4 | Negative | Online Inquiry |
KO26222 | TRIM46 Knockout cell line (HEK293) | Human | TRIM46 | 1:3~1:6 | Negative | Online Inquiry |
KO26223 | TRIM46 Knockout cell line (A549) | Human | TRIM46 | 1:3~1:4 | Negative | Online Inquiry |
TRIM46 Gene Knockout Cell Lines are genetically engineered human cell lines specifically designed for the study of the TRIM46 gene, which plays a crucial role in various cellular processes, including cell proliferation, differentiation, and signal transduction. By disrupting the TRIM46 gene, these knockout cell lines enable researchers to investigate the functional consequences of its absence, offering insights into its involvement in cellular mechanisms and potential implications in disease pathology.
The TRIM46 gene encodes a member of the tripartite motif (TRIM) family of proteins, known for their roles in mediating protein interactions and post-translational modifications. The knockout of TRIM46 facilitates the comprehensive analysis of its regulatory networks and downstream signaling pathways. Researchers can employ these cell lines to explore the effects of TRIM46 loss on processes such as immune responses, cancer development, and neurological disorders, proving invaluable for advanced studies in molecular biology and genetics.
The scientific importance of TRIM46 Gene Knockout Cell Lines lies in their vast applications in both research and clinical settings. These models provide a platform for drug discovery, biomarker identification, and the development of targeted therapies. They also serve as essential tools for validation of hypotheses regarding TRIM46’s role in diverse pathological conditions, helping to bridge the gap between basic science and applied medicine.
Compared to alternative models, TRIM46 Gene Knockout Cell Lines offer enhanced specificity and reliability due to their precise genetic manipulation. This specificity reduces background variability and increases experimental reproducibility, addressing common challenges in cellular research. Moreover, these knockout lines come with robust validation protocols, ensuring high-quality outputs that contribute to the integrity of scientific findings.
For researchers and clinicians, utilizing TRIM46 Gene Knockout Cell Lines not only accelerates the understanding of gene function and regulation but also paves the way for innovative therapeutic strategies. The versatility and specificity of these cell lines make them an essential addition to any laboratory focused on cutting-edge research.
Our company, recognized for its expertise in genetic engineering and commitment to advancing scientific research, offers a range of high-quality biological products, including TRIM46 Gene Knockout Cell Lines. With a strong focus on innovation and scientific integrity, we are dedicated to providing researchers with tools that empower breakthroughs in biological science.
Please note that all services are for research use only. Not intended for any clinical use.
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