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TRIM44 Knockout Cell Lines

Gene: TRIM44

Official Full Name: tripartite motif containing 44provided by HGNC

Gene Summary: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, namely a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13059 TRIM44 Knockout cell line (HeLa) Human TRIM44 1:3~1:6 Negative Online Inquiry
KO13060 TRIM44 Knockout cell line (HCT 116) Human TRIM44 1:2~1:4 Negative Online Inquiry
KO13061 TRIM44 Knockout cell line (HEK293) Human TRIM44 1:3~1:6 Negative Online Inquiry
KO13062 TRIM44 Knockout cell line (A549) Human TRIM44 1:3~1:4 Negative Online Inquiry

Background

TRIM44 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the TRIM44 gene's role in various biological processes. These cell lines are developed using advanced CRISPR-Cas9 technology to effectively disrupt the TRIM44 gene, allowing researchers to investigate its function and involvement in cellular pathways, disease mechanisms, and therapeutic responses.

The primary function of these knockout cell lines is to provide a controlled environment for studying the effects of TRIM44 deficiency on cellular behavior, including proliferation, differentiation, and response to stress or drugs. By removing the TRIM44 gene, these cell lines help elucidate the gene’s contributions to processes such as apoptosis, immune responses, and cancer progression, revealing significant insights into host-pathogen interactions and potential therapeutic targets.

The scientific importance of TRIM44 Gene Knockout Cell Lines lies in their vast applications in both research and clinical settings. They serve as essential tools in cancer research, drug development, and precision medicine by enabling the evaluation of TRIM44's implications in tumor biology and treatment resistance. Furthermore, these knockout models can advance the understanding of autoimmune diseases, highlighting pathways that contribute to immune dysregulation.

Compared to alternatives like conventional knockout models, TRIM44 Gene Knockout Cell Lines offer distinct advantages such as ease of use, reproducibility, and the ability to create multiple knockout variants. This precision significantly reduces experimental variability and accelerates the research timeline, allowing scientists to achieve reliable results more efficiently.

For researchers, clinicians, and industry professionals, investing in TRIM44 Gene Knockout Cell Lines represents a valuable opportunity to drive innovation in understanding complex biological systems. The knockout models empower users to explore new therapeutic avenues and improve patient outcomes. As a leading provider of advanced biological products, our company is committed to delivering high-quality, scientifically validated tools that meet the evolving needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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