Gene: TRIM31
Official Full Name: tripartite motif containing 31provided by HGNC
Gene Summary: This gene encodes a protein that functions as an E3 ubiquitin-protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31249 | TRIM31 Knockout cell line (A549) | Human | TRIM31 | 1:3~1:4 | Negative | Online Inquiry |
TRIM31 Gene Knockout Cell Lines are genetically modified cell lines in which the TRIM31 gene has been precisely disrupted, creating an invaluable tool for scientific research. TRIM31, a member of the tripartite motif (TRIM) family of proteins, plays a crucial role in various cellular processes, including protein ubiquitination, signal transduction, and immune responses. By employing CRISPR-Cas9 gene editing technology, these knockout cell lines allow researchers to elucidate the specific biological functions of TRIM31 and its involvement in pathways such as inflammation and tumorigenesis.
The primary function of TRIM31 Gene Knockout Cell Lines is to facilitate studies aimed at understanding the pathological implications of TRIM31 deficiency. The absence of this gene reveals its role in disease models and helps clarify cellular mechanisms that may lead to novel therapeutic targets. In clinical research, using TRIM31 knockout cells can enhance our understanding of cancer biology, autoimmunity, and metabolic disorders, making these cells highly relevant in both fundamental and translational research.
One of the distinct advantages of using these knockout cell lines over traditional models is their ability to provide insights into gene function without the confounding effects of alternative genes or pathways. Researchers can conduct more controlled experiments which are crucial for obtaining reliable data. Additionally, the high specificity of CRISPR-Cas9 technology minimizes off-target effects, leading to robust experimental outcomes.
For researchers, clinicians, and biotechnology companies, the TRIM31 Gene Knockout Cell Lines represent a powerful resource for dissecting gene function, validating therapeutic targets, and developing innovative treatments. Investing in these cell lines not only accelerates research timelines but also aligns projects with cutting-edge genomic methodologies.
With a commitment to advancing biotechnological research and a deep understanding of the complexities of genetic modifications, our company excels in providing high-quality research tools that empower scientists worldwide to make significant discoveries in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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