Gene: TRIM29
Official Full Name: tripartite motif containing 29provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29020 | TRIM29 Knockout cell line (HeLa) | Human | TRIM29 | 1:3~1:6 | Negative | Online Inquiry |
KO29021 | TRIM29 Knockout cell line (A549) | Human | TRIM29 | 1:3~1:4 | Negative | Online Inquiry |
TRIM29 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research focused on understanding the functional roles of the TRIM29 gene, a member of the tripartite motif (TRIM) family that plays crucial roles in diverse cellular processes, including immune response and tumorigenesis. By utilizing CRISPR-Cas9 technology, our TRIM29 knockout cell lines enable precise elimination of the TRIM29 gene, facilitating the study of its downstream effects and interacting pathways.
Functionally, these cell lines serve as invaluable models for dissecting the impact of TRIM29 loss on cellular behavior, gene expression regulation, and signaling pathways. Researchers can explore how the absence of TRIM29 influences cellular proliferation, apoptosis, and response to environmental stressors, thereby providing insights critical for developing targeted therapies against cancers and autoimmune diseases where TRIM29 dysregulation is implicated.
The scientific importance of TRIM29 Gene Knockout Cell Lines extends to their application in both fundamental and translational research settings. In academic research, they enable the examination of gene function and elucidate mechanisms of pathology, while in clinical research, these models support the identification of potential therapeutic targets and biomarkers for patient stratification.
What sets our TRIM29 knockout cell lines apart is their high specificity and efficiency achieved through our proprietary knockout process, minimizing off-target effects that can confound experimental results. Additionally, the robustness of these cell lines assures reproducibility and reliability, making them a preferred choice for researchers entering the realm of genomic studies.
For researchers and clinicians seeking to deepen their understanding of TRIM29-related pathways, our product provides a unique opportunity to bridge gaps in knowledge that are pivotal for advances in precision medicine. Our commitment to quality and scientific rigor is backed by years of expertise in the development of innovative biological products, ensuring that your research efforts are supported by the most reliable tools available in the market.
Please note that all services are for research use only. Not intended for any clinical use.
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