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TRIM11 Knockout Cell Lines

Gene: TRIM11

Official Full Name: tripartite motif containing 11provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25758 TRIM11 Knockout cell line (HeLa) Human TRIM11 1:3~1:6 Negative Online Inquiry
KO25759 TRIM11 Knockout cell line (HCT 116) Human TRIM11 1:2~1:4 Negative Online Inquiry
KO25760 TRIM11 Knockout cell line (HEK293) Human TRIM11 1:3~1:6 Negative Online Inquiry
KO25761 TRIM11 Knockout cell line (A549) Human TRIM11 1:3~1:4 Negative Online Inquiry

Background

TRIM11 Gene Knockout Cell Lines are specialized cellular models engineered to lack the TRIM11 gene, which encodes a member of the tripartite motif (TRIM) protein family involved in various cellular processes, including immune regulation and antiviral defense. The precise deletion of the TRIM11 gene utilizing CRISPR/Cas9 technology facilitates the study of its biological functions and delineates its role in cellular signaling pathways. These knockout cell lines serve as powerful tools in elucidating the molecular mechanisms associated with TRIM11's involvement in disease states, particularly in cancer biology and infection responses.

The fundamental function of TRIM11 in ubiquitination and protein modification underscores its significance in cellular homeostasis and response mechanisms. By studying these knockout models, researchers can investigate the downstream effects resulting from the absence of TRIM11, offering insights into its potential as a therapeutic target. The applications extend to various research domains, including oncology, virology, and neurobiology, making them invaluable for both academic and clinical research initiatives.

What sets TRIM11 Gene Knockout Cell Lines apart from traditional cell models is their high specificity and efficiency, achieved through precise gene editing techniques. Unlike random mutagenesis or chemical inhibitors that may yield off-target effects, these knockout lines provide a reliable system for dissecting gene function without confounding variables. Moreover, they enable researchers to better understand gene-environment interactions and contribute to the development of targeted therapies.

These cell lines are particularly valuable to researchers and clinicians seeking to deepen their understanding of TRIM11's contribution to various pathologies. By offering a clear view of the biological implications of TRIM11 deficiency, users can accelerate the discovery of novel therapeutic strategies. Our company, with extensive experience in cell line development and genetic engineering, is committed to providing high-quality, validated biological products that support cutting-edge research and clinical advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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