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TRERF1 Knockout Cell Lines

Gene: TRERF1

Official Full Name: transcriptional regulating factor 1provided by HGNC

Gene Summary: This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13067 TRERF1 Knockout cell line (HeLa) Human TRERF1 1:3~1:6 Negative Online Inquiry
KO13068 TRERF1 Knockout cell line (HCT 116) Human TRERF1 1:2~1:4 Negative Online Inquiry
KO13069 TRERF1 Knockout cell line (HEK293) Human TRERF1 1:3~1:6 Negative Online Inquiry
KO13070 TRERF1 Knockout cell line (A549) Human TRERF1 1:3~1:4 Negative Online Inquiry

Background

TRERF1 Gene Knockout Cell Lines are specifically engineered cellular models that have had the TRERF1 gene effectively disrupted. This targeted knockout enables researchers to investigate the functional role of the TRERF1 protein in various biological pathways and disease processes. The TRERF1 gene is implicated in crucial cellular functions, including gene regulation, stress response, and cellular proliferation. Through the mechanism of gene knockout, these cell lines facilitate the study of how loss of TRERF1 expression influences these cellular processes, providing valuable insights into its contribution to disease pathogenesis and potential therapeutic targets.

The scientific importance of TRERF1 Gene Knockout Cell Lines cannot be overstated, as they serve as an essential tool for exploring the molecular underpinnings of various disorders, including cancer and neurodegenerative diseases. In clinical research settings, these cell lines can be utilized to evaluate potential drug candidates by examining their effects on cellular behavior in the absence of TRERF1. Furthermore, they can support the development of novel therapeutic strategies aimed at modulating the pathways in which TRERF1 is involved.

Compared to traditional methods of studying gene function, such as siRNA or CRISPR interference, the use of knockout cell lines offers distinct advantages. These models provide a stable and reproducible system for examining long-term effects of gene loss, whereas transient techniques might produce variable results. Additionally, our TRERF1 Gene Knockout Cell Lines are optimized for high transfection efficiency and low off-target effects, augmenting their reliability for in-depth experimental procedures.

For researchers and clinicians aiming to enhance their understanding of complex cellular mechanisms or to develop targeted treatments, TRERF1 Gene Knockout Cell Lines represent an invaluable resource. Their ability to dissect the roles of TRERF1 in health and disease positions them as a superior choice for advancing biomedical research.

At our company, we pride ourselves on our cutting-edge methods and commitment to providing exceptional biological products, ensuring that our clients have access to the highest quality tools necessary for their research and clinical needs.

Please note that all services are for research use only. Not intended for any clinical use.

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