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TPGS2 Knockout Cell Lines

Gene: TPGS2

Official Full Name: tubulin polyglutamylase complex subunit 2provided by HGNC

Gene Summary: This gene encodes a protein that is a component of the neuronal polyglutamylase complex, which plays a role in post-translational addition of glutamate residues to C-terminal tubulin tails. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28592 TPGS2 Knockout cell line (HeLa) Human TPGS2 1:3~1:6 Negative Online Inquiry
KO28593 TPGS2 Knockout cell line (HCT 116) Human TPGS2 1:2~1:4 Negative Online Inquiry
KO28594 TPGS2 Knockout cell line (HEK293) Human TPGS2 1:3~1:6 Negative Online Inquiry
KO28595 TPGS2 Knockout cell line (A549) Human TPGS2 1:3~1:4 Negative Online Inquiry

Background

TPGS2 Gene Knockout Cell Lines are genetically modified cell lines designed specifically to investigate the role of the TPGS2 gene, a critical player in the mechanisms of drug metabolism and delivery. These cell lines have been engineered through CRISPR-Cas9 technology to knockout the TPGS2 gene, facilitating in-depth studies of its physiological and pathological functions.

The primary function of TPGS2 involves its influence on cellular drug transport mechanisms, which is essential for enhancing the bioavailability and efficacy of therapeutic agents. By knocking out TPGS2, researchers can study alterations in drug uptake, metabolism, and the resultant pharmacological effects, thus providing valuable insights into the design of more effective drug formulations that may enhance patient outcomes.

The scientific significance of TPGS2 Gene Knockout Cell Lines is underscored by their wide-ranging applications in both research and clinical settings, particularly in pharmacology, toxicology, and molecular biology. Researchers engage these cell lines to elucidate drug resistance mechanisms in cancer cells or to optimize drug delivery systems that maximize therapeutic performance while minimizing adverse effects.

Compared to traditional cell lines, TPGS2 Gene Knockout Cell Lines offer unique advantages, including a highly specific focus on TPGS2 pathways and mechanisms, allowing for precise and reproducible experimental designs. Furthermore, these cell lines are optimized for high-throughput screening, streamlining the drug discovery process significantly.

For researchers and clinicians, the adoption of TPGS2 Gene Knockout Cell Lines represents a powerful tool for advancing therapeutic strategies, potentially leading to breakthroughs in personalized medicine. The ability to conduct targeted experiments in a controlled environment enhances the understanding of drug interactions, offering a compelling reason to incorporate this product into their research toolkit.

As a leader in the field of genetic engineering, our company prides itself on providing cutting-edge biological products that support pioneering research efforts. With a commitment to quality and innovation, we ensure that our offerings, including TPGS2 Gene Knockout Cell Lines, meet the rigorous demands of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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