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TPD52L2 Knockout Cell Lines

Gene: TPD52L2

Official Full Name: TPD52 like 2provided by HGNC

Gene Summary: This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34958 TPD52L2 Knockout cell line (HeLa) Human TPD52L2 1:3~1:6 Negative Online Inquiry
KO34959 TPD52L2 Knockout cell line (HCT 116) Human TPD52L2 1:2~1:4 Negative Online Inquiry
KO34960 TPD52L2 Knockout cell line (HEK293) Human TPD52L2 1:3~1:6 Negative Online Inquiry
KO34961 TPD52L2 Knockout cell line (A549) Human TPD52L2 1:3~1:4 Negative Online Inquiry

Background

TPD52L2 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the TPD52L2 gene, which is implicated in various cellular processes including cancer progression, cell proliferation, and apoptosis. These knockout cell lines enable researchers to investigate the physiological roles of TPD52L2 by systematically removing its expression, thereby elucidating its contribution to disease mechanisms.

The key function of these cell lines lies in their ability to serve as vital tools for functional genomics studies. Researchers employ gene-editing techniques, such as CRISPR-Cas9, to create precise deletions of the TPD52L2 gene, resulting in observable phenotypic changes. This allows for in-depth analysis of TPD52L2's interactions, signaling pathways, and potential compensatory mechanisms in cellular contexts, offering insights into its role in tumor biology and response to therapy.

The scientific importance of TPD52L2 knockout cell lines spans across various fields, including cancer research, drug discovery, and genetic studies. They can be used in preclinical models to assess how the absence of TPD52L2 affects cell behavior in response to oncogenic stimuli or therapeutic agents, providing critical data that drives the development of targeted treatments.

Compared to conventional cell lines that express the TPD52L2 gene, our knockout variants offer a clear advantage by allowing researchers to observe the phenotypic effects of gene loss without confounding factors from residual gene expression. This specificity enhances the reliability of experimental results and accelerates hypothesis testing.

For researchers and clinicians, the TPD52L2 Gene Knockout Cell Lines represent a valuable resource for advancing our understanding of cancer biology and therapeutic resistance mechanisms. Their targeted application can lead to breakthroughs in treatment strategies aimed at mitigating the roles of this gene in tumorigenesis.

As a company committed to providing high-quality biological products, we pride ourselves on our extensive expertise in genetic engineering and cell line development. Our TPD52L2 Gene Knockout Cell Lines are rigorously validated to ensure the utmost precision and reproducibility demanded by cutting-edge research.

Please note that all services are for research use only. Not intended for any clinical use.

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