Gene: TPD52L1
Official Full Name: TPD52 like 1provided by HGNC
Gene Summary: This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34946 | TPD52L1 Knockout cell line (HeLa) | Human | TPD52L1 | 1:3~1:6 | Negative | Online Inquiry |
KO34947 | TPD52L1 Knockout cell line (HCT 116) | Human | TPD52L1 | 1:2~1:4 | Negative | Online Inquiry |
KO34948 | TPD52L1 Knockout cell line (HEK293) | Human | TPD52L1 | 1:3~1:6 | Negative | Online Inquiry |
KO34949 | TPD52L1 Knockout cell line (A549) | Human | TPD52L1 | 1:3~1:4 | Negative | Online Inquiry |
TPD52L1 Gene Knockout Cell Lines are specifically engineered cells that lack the expression of the TPD52L1 gene, providing a valuable tool for investigating the role of this gene in cellular processes and disease mechanisms. The TPD52L1 gene encodes a protein implicated in various biological functions, including cell proliferation, apoptosis, and tumor progression. By utilizing these knockout cell lines, researchers can effectively elucidate the specific contributions and pathways involving TPD52L1, offering insights into its potential oncogenic properties and involvement in cancer biology.
The primary function of TPD52L1 Gene Knockout Cell Lines is to facilitate loss-of-function studies, allowing scientists to observe phenotypic changes that occur in the absence of TPD52L1. Through techniques such as Western blotting, RT-qPCR, and functional assays, researchers can evaluate alterations in cell signaling pathways, adhesion properties, and response to therapeutic agents. This unique mechanism of study enhances understanding of TPD52L1's role in oncogenesis, potentially leading to the development of novel therapeutic strategies targeting TPD52L1-related pathways.
The importance of TPD52L1 knockout models extends to both basic research and clinical settings. These cell lines provide a crucial platform for drug discovery and the validation of therapeutic targets, particularly in oncology, where TPD52L1 may play a significant role in tumorigenesis. Furthermore, this tool supports elucidation of cancer-related pathways, paving the way for advancements in personalized medicine approaches.
What sets our TPD52L1 Gene Knockout Cell Lines apart from competitors is the stringent validation process they undergo, ensuring high specificity and reproducibility in experimental results. These lines are generated using state-of-the-art CRISPR technology, which enables precise modifications while minimizing off-target effects. Additionally, our commitment to maintaining a rigorous quality assurance program guarantees that researchers receive reliable products that enhance experimental rigor.
For researchers and clinicians seeking to deepen their understanding of cancer biology or develop innovative treatments, TPD52L1 Gene Knockout Cell Lines represent an indispensable resource. By leveraging this cutting-edge product, users can accelerate discoveries in cellular mechanisms and drug responsiveness.
Our company boasts extensive expertise in producing high-quality biological products, and we continuously invest in research and development to provide researchers with the tools necessary to advance scientific knowledge. With a dedication to excellence and innovation, we are proud to support the scientific community in its quest for transformative discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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