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TPBG Knockout Cell Lines

Gene: TPBG

Official Full Name: trophoblast glycoproteinprovided by HGNC

Gene Summary: This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09942 TPBG Knockout cell line (HeLa) Human TPBG 1:3~1:6 Negative Online Inquiry
KO09943 TPBG Knockout cell line (HCT 116) Human TPBG 1:2~1:4 Negative Online Inquiry
KO09944 TPBG Knockout cell line (HEK293) Human TPBG 1:3~1:6 Negative Online Inquiry
KO09945 TPBG Knockout cell line (A549) Human TPBG 1:3~1:4 Negative Online Inquiry

Background

TPBG Gene Knockout Cell Lines are specialized cellular models engineered to systematically disrupt the expression of the TPBG gene, which encodes for a protein involved in critical biological processes such as cell proliferation and signal transduction. By employing technologies such as CRISPR/Cas9 or homologous recombination, our cell lines provide researchers with a valuable tool to study the functional role of TPBG in various cellular contexts.

The primary mechanism of TPBG Gene Knockout Cell Lines centers around gene editing techniques that create precise deletions or mutations within the TPBG gene. This knockout approach allows for the analysis of resulting phenotypic changes and downstream molecular effects, enabling scientists to better understand the gene's contributions to cellular behavior, disease models, and therapeutic targets. These cell lines can also serve as platforms for high-throughput screening of potential drug candidates.

In terms of scientific significance, TPBG Gene Knockout Cell Lines have applications in both research and clinical settings, particularly in oncology, developmental biology, and regenerative medicine. By elucidating the role of TPBG in disease processes, researchers can reveal novel pathways for intervention—paving the way for advancements in targeted therapies.

What sets our TPBG Gene Knockout Cell Lines apart from other gene knockout models is their unparalleled specificity and reliability, coupled with exceptional batch-to-batch consistency. This level of meticulous design ensures reproducibility in experiments, reducing variability that could confound results in high-stakes research environments.

For researchers and clinicians alike, the capacity to manipulate and analyze the TPBG gene in human-derived cell models unlocks significant potential for groundbreaking discoveries and therapeutic developments. Our product not only enhances experimental accuracy but also fosters innovative applications that can lead to improved patient outcomes.

With our company’s extensive expertise in cellular engineering and commitment to advancing biotechnology, we deliver high-quality biological products designed to empower scientific exploration and innovation. Our dedication to supporting the research community ensures that you are equipped with cutting-edge tools to drive your findings forward.

Please note that all services are for research use only. Not intended for any clinical use.

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