Gene: TOX
Official Full Name: thymocyte selection associated high mobility group boxprovided by HGNC
Gene Summary: The protein encoded by this gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.[provided by RefSeq, Apr 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09445 | TOX Knockout cell line (HeLa) | Human | TOX | 1:3~1:6 | Negative | Online Inquiry |
KO09446 | TOX Knockout cell line (HEK293) | Human | TOX | 1:3~1:6 | Negative | Online Inquiry |
TOX Gene Knockout Cell Lines are advanced biological tools that facilitate the study of gene function and regulation by providing researchers with specific cellular models in which the TOX gene has been inactivated. These engineered cell lines are derived using CRISPR-Cas9 gene editing technology, leading to precise deletions that allow for the observation of the resultant phenotypic changes, thereby elucidating the role of TOX in various biological processes such as immune response and T cell development.
The primary function of TOX Gene Knockout Cell Lines is to serve as a platform for functional assays, enabling investigations into the cellular pathways influenced by the TOX gene. By observing the cellular behavior in the absence of TOX, researchers can identify downstream targets, signaling cascades, and potential therapeutic interventions for diseases where TOX plays a critical role, such as autoimmune disorders and cancer.
In a clinical or research setting, these knockout cell lines are invaluable for validating drug targets and dissecting disease mechanisms. As such, they contribute significantly to advancing personalized medicine and the development of novel therapeutics. Researchers can leverage these models to streamline drug discovery processes and enhance translational research efforts.
A considerable advantage of TOX Gene Knockout Cell Lines over traditional cell lines is their specificity; they allow for the targeted exploration of gene function without the confounding effects associated with off-target mutations. This specificity ensures reproducibility in experiments, leading to more reliable data generation. Furthermore, these knockout cell lines can be readily adapted to various assays, including high-throughput screening and functional genomics.
The value of TOX Gene Knockout Cell Lines extends beyond basic research; they are essential tools in the quest to better understand genetic diseases and develop impactful treatment strategies. Our company specializes in providing high-quality, meticulously validated biological products, reflecting our commitment to driving innovation in scientific research. With our expertise and dedication to quality, researchers and clinicians can confidently utilize our TOX Gene Knockout Cell Lines to uncover new insights into gene functionality and disease mechanisms, ultimately contributing to the advancement of healthcare and improved patient outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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