Gene: TOMM40L
Official Full Name: translocase of outer mitochondrial membrane 40 likeprovided by HGNC
Gene Summary: Predicted to enable protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25167 | TOMM40L Knockout cell line (HeLa) | Human | TOMM40L | 1:3~1:6 | Negative | Online Inquiry |
KO25168 | TOMM40L Knockout cell line (HCT 116) | Human | TOMM40L | 1:2~1:4 | Negative | Online Inquiry |
KO25169 | TOMM40L Knockout cell line (HEK293) | Human | TOMM40L | 1:3~1:6 | Negative | Online Inquiry |
KO25170 | TOMM40L Knockout cell line (A549) | Human | TOMM40L | 1:3~1:4 | Negative | Online Inquiry |
TOMM40L Gene Knockout Cell Lines are genetically engineered cell lines in which the TOMM40L gene has been selectively disrupted. This gene is critical for mitochondrial protein import and plays a significant role in cellular energy metabolism. By utilizing CRISPR-Cas9 technology, our TOMM40L knockout cell lines provide researchers with a precise model to study the functional implications of TOMM40L deficiency, allowing for a deeper understanding of its role in human diseases, particularly those related to bioenergetics and neurodegenerative conditions.
The primary function of these cell lines is to facilitate investigations into the molecular pathways influenced by TOMM40L. By observing changes in cellular behavior, metabolism, and survival in these knockout models, researchers can elucidate the gene's involvement in mitochondrial dynamics and overall cell viability. These insights are invaluable in both basic research and translational science, paving the way for potential therapeutic interventions in diseases such as Alzheimer's, where mitochondrial dysfunction is a known contributing factor.
In terms of scientific importance, TOMM40L knockout cell lines hold tremendous potential in pharmacological studies, gene therapy research, and in developing novel biomarkers for disease progression. They offer a unique platform for testing the efficacy of therapeutic agents targeting mitochondrial pathways, providing robust data that standard cell lines cannot.
Unique selling points of our TOMM40L Gene Knockout Cell Lines lie in their high specificity, reproducibility, and validated background, compared to traditional knockout methods. This means that researchers can trust the results obtained from these cell lines, reducing variability in experimental outcomes, which is often seen in other models.
The value this product offers to researchers and clinicians is substantial; with the need for reliable and effective model systems in the era of precision medicine, our TOMM40L knockout cell lines stand out as an essential tool for advancing understanding and treatment of mitochondrial-related diseases.
With years of expertise in gene editing technologies and a commitment to innovative biological products, our company ensures that researchers have access to the highest quality cell lines, supporting the pursuit of groundbreaking advancements in cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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