Gene: TOB2
Official Full Name: transducer of ERBB2, 2provided by HGNC
Gene Summary: TOB2 belongs to the TOB (see TOB1; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.[supplied by OMIM, Apr 2004]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31539 | TOB2 Knockout cell line (HeLa) | Human | TOB2 | 1:3~1:6 | Negative | Online Inquiry |
KO31540 | TOB2 Knockout cell line (HCT 116) | Human | TOB2 | 1:2~1:4 | Negative | Online Inquiry |
KO31541 | TOB2 Knockout cell line (HEK293) | Human | TOB2 | 1:3~1:6 | Negative | Online Inquiry |
KO31542 | TOB2 Knockout cell line (A549) | Human | TOB2 | 1:3~1:4 | Negative | Online Inquiry |
TOB2 Gene Knockout Cell Lines are specialized biological products developed to facilitate the exploration of TOB2 gene function and its broader implications in cellular processes. These cell lines have been genetically engineered to maintain a knockout of the TOB2 gene, thereby allowing researchers to study the resultant phenotypic changes in a controlled environment. The TOB2 gene is known to play critical roles in regulating cell growth, apoptosis, and immune responses; thus, its alteration can yield insights into various developmental and pathophysiological conditions.
The key mechanism behind TOB2 knockout cell lines lies in their ability to provide a platform for investigating the specific contributions of the TOB2 gene to cellular behavior. By comparing the functional characteristics of these knockout cells with their wild-type counterparts, researchers can elucidate molecular pathways and signaling cascades influenced by TOB2. Such insights are invaluable for understanding the gene's role in diseases, including cancer and autoimmune disorders.
Scientifically, TOB2 Gene Knockout Cell Lines are instrumental for both laboratory research and potential therapeutic development. They provide a reliable model system for drug screening, functional genomics, and studies examining gene interactions. Their application in preclinical settings can expedite the discovery of novel therapeutic targets and aid in the validation of biomarker hypotheses.
Compared to other cell line models or overexpression systems, the TOB2 knockout approach offers distinct advantages, including precise gene disruption, minimized off-target effects, and a more accurate reflection of gene function in a relevant cellular context. This specificity enhances the reliability of experimental outcomes, making these cell lines an essential tool for researchers pursuing high-quality, reproducible results.
For researchers and clinicians, the value of TOB2 Gene Knockout Cell Lines is clear—they provide a cutting-edge technological resource with the potential to advance our understanding of genetic contributions to disease. By harnessing this product, users can enhance the rigor of their experimental designs, drive innovation in their research, and accelerate the pace of discovery.
Our company specializes in providing high-quality biological products, backed by extensive expertise in genomic technologies and cell line developments. We are committed to supporting the scientific community by granting access to advanced tools that facilitate groundbreaking research and contribute to the advancement of knowledge in the biological sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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