Gene: TNFAIP8L3
Official Full Name: TNF alpha induced protein 8 like 3provided by HGNC
Gene Summary: Predicted to enable phosphatidylinositol binding activity and phosphatidylinositol transfer activity. Predicted to be involved in 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process; phospholipid transport; and positive regulation of ERK1 and ERK2 cascade. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13128 | TNFAIP8L3 Knockout cell line (HeLa) | Human | TNFAIP8L3 | 1:3~1:6 | Negative | Online Inquiry |
KO13129 | TNFAIP8L3 Knockout cell line (HCT 116) | Human | TNFAIP8L3 | 1:2~1:4 | Negative | Online Inquiry |
KO13130 | TNFAIP8L3 Knockout cell line (HEK293) | Human | TNFAIP8L3 | 1:3~1:6 | Negative | Online Inquiry |
KO13131 | TNFAIP8L3 Knockout cell line (A549) | Human | TNFAIP8L3 | 1:3~1:4 | Negative | Online Inquiry |
TNFAIP8L3 Gene Knockout Cell Lines are a sophisticated biological product engineered to facilitate the study of this specific gene's function and its role in various biological processes. The TNFAIP8L3 gene is implicated in regulating immune responses and has been associated with several pathological conditions, including inflammation and cancer. By creating knockout cell lines, researchers can effectively eliminate the expression of TNFAIP8L3, providing insights into its biological significance and cellular mechanisms.
These knockout cell lines operate by employing CRISPR-Cas9 technology to introduce specific mutations, leading to a complete loss of gene function. This precise genetic editing technique enables researchers to investigate the downstream effects of TNFAIP8L3 absence on cellular behavior, signal transduction pathways, and gene expression profiles. The model offers a robust platform for understanding disease mechanisms and discovering novel therapeutic targets.
The scientific importance of TNFAIP8L3 Gene Knockout Cell Lines lies in their wide applications in both research and clinical settings. These cell lines serve as invaluable tools for elucidating the pathways involving TNFAIP8L3, facilitating drug discovery and development. Their use is particularly critical in the exploration of therapies for autoimmune disorders and cancer, where understandings of immune modulation are essential.
Compared to traditional gene silencing methods, such as RNA interference, TNFAIP8L3 Gene Knockout Cell Lines provide a more permanent and specific approach to gene inactivation. This specificity allows for clearer interpretation of experimental results, minimizing off-target effects that may confound findings. Moreover, these cell lines are designed to be easily manipulated, versatile, and compatible with high-throughput screening methods, enhancing their utility in lab settings.
Researchers and clinicians can greatly benefit from the insights gained through studies utilizing TNFAIP8L3 Gene Knockout Cell Lines, as they enable the exploration of fundamental biological questions and the potential development of targeted therapies. With a commitment to advancing scientific research, our company leverages state-of-the-art technologies to deliver high-quality biological products that empower scientists in their quest for knowledge and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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