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TMF1 Knockout Cell Lines

Gene: TMF1

Official Full Name: TATA element modulatory factor 1provided by HGNC

Gene Summary: Enables nuclear androgen receptor binding activity and nuclear receptor coactivator activity. Involved in androgen receptor signaling pathway and positive regulation of transcription by RNA polymerase II. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34985 TMF1 Knockout cell line (HeLa) Human TMF1 1:3~1:6 Negative Online Inquiry
KO34986 TMF1 Knockout cell line (HCT 116) Human TMF1 1:2~1:4 Negative Online Inquiry
KO34987 TMF1 Knockout cell line (HEK293) Human TMF1 1:3~1:6 Negative Online Inquiry
KO34988 TMF1 Knockout cell line (A549) Human TMF1 1:3~1:4 Negative Online Inquiry

Background

TMF1 Gene Knockout Cell Lines are genetically engineered cell lines in which the TMF1 (Tumor Modulator Factor 1) gene has been selectively disrupted. This innovative product provides researchers with a powerful tool to study the functional role of TMF1 in various biological processes, including tumorigenesis, apoptosis, and cellular differentiation. The knockout is achieved through targeted gene editing techniques, allowing for precise and reproducible genetic modifications that facilitate in-depth investigation of TMF1's contributions to cell biology.

The primary function of these cell lines is to enable the examination of phenotypic changes and molecular pathways that are influenced by the absence of TMF1. Researchers can utilize these cell lines to explore how TMF1 impacts cancer cell behavior, affecting proliferation, migration, and treatment response, thereby elucidating its role in cancer biology. By investigating these mechanisms, researchers can gain insights into potential therapeutic targets and biomarkers relevant to various malignancies.

The scientific importance of TMF1 Gene Knockout Cell Lines is underscored by their broad applications in both basic and applied research settings. They can be employed in drug discovery and development, studies of cellular signaling pathways, and in understanding genetic disorders associated with TMF1 dysregulation. The ability to create isogenic cell models enhances the reliability of experimental results, making them invaluable for translational research.

Compared to traditional cell lines, TMF1 Gene Knockout Cell Lines offer a unique advantage by providing a clear model to delineate the function of the TMF1 gene under study. These knockout lines reduce background variability related to gene expression, resulting in more robust and interpretable outcomes during experimental observations.

The value of TMF1 Gene Knockout Cell Lines to researchers and clinicians lies in their ability to facilitate target validation, system biology studies, and the exploration of novel therapeutic approaches that may emerge from their insights. With these cell lines, researchers are equipped to advance the understanding of complex biological systems and develop more effective treatment strategies.

As a leader in providing innovative biological products, our company is committed to delivering high-quality research tools that empower the scientific community. Our expertise in gene editing technologies and commitment to excellence ensure that you receive reliable and effective resources to further your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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