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TMEM97 Knockout Cell Lines

Gene: TMEM97

Official Full Name: transmembrane protein 97provided by HGNC

Gene Summary: TMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels (Bartz et al., 2009 [PubMed 19583955]).[supplied by OMIM, Aug 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27624 TMEM97 Knockout cell line (HeLa) Human TMEM97 1:3~1:6 Negative Online Inquiry
KO27625 TMEM97 Knockout cell line (HCT 116) Human TMEM97 1:2~1:4 Negative Online Inquiry
KO27626 TMEM97 Knockout cell line (HEK293) Human TMEM97 1:3~1:6 Negative Online Inquiry
KO27627 TMEM97 Knockout cell line (A549) Human TMEM97 1:3~1:4 Negative Online Inquiry

Background

TMEM97 Gene Knockout Cell Lines refer to genetically modified cellular models in which the TMEM97 gene has been systematically disrupted. TMEM97 is implicated in various physiological processes, including lipid metabolism and cellular response to stress. By creating knockout versions of this gene, researchers can investigate its specific roles in cellular function, enabling a deeper understanding of signaling pathways and molecular mechanisms associated with metabolic disorders and neurodegenerative diseases.

These cell lines function by providing a controlled environment in which the absence of TMEM97 can highlight its direct effects on cellular processes such as protein trafficking, endocytosis, and interaction with cholesterol. This creates opportunities for studying the gene's involvement in pathophysiological conditions, including Alzheimer’s disease and cancer progression. Researchers often utilize these models to screen potential therapeutic compounds, helping to delineate new avenues for drug discovery.

The scientific importance of TMEM97 Gene Knockout Cell Lines extends beyond basic research, making them crucial tools in translational medicine. Their applications range from fundamental biology studies to high-throughput drug screening in clinical environments, allowing scientists to evaluate therapeutic strategies effectively.

Compared to traditional knockdown approaches, our knockout cell lines provide a more definitive insight into gene function, as they completely eliminate TMEM97 expression rather than merely reducing it. This leads to clearer interpretative results in experimental outcomes, making the data derived from these cell lines more robust and reliable. Moreover, our commitment to high-quality production practices ensures that these cell lines are validated and reproducible, minimizing variability in research outcomes.

For researchers and clinicians seeking to advance the understanding of TMEM97-related pathways and their implications in human disease, our TMEM97 Gene Knockout Cell Lines are an invaluable resource. Backed by our extensive expertise in genetic modification and commitment to innovation, our products are designed to enhance experimental accuracy and provide pivotal insights through cutting-edge research tools.

Please note that all services are for research use only. Not intended for any clinical use.

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