Home / TMEM8B Knockout Cell Lines

TMEM8B Knockout Cell Lines

Gene: TMEM8B

Official Full Name: transmembrane protein 8Bprovided by HGNC

Gene Summary: Involved in cell-matrix adhesion. Located in cell surface and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22224 TMEM8B Knockout cell line (HeLa) Human TMEM8B 1:3~1:6 Negative Online Inquiry
KO22225 TMEM8B Knockout cell line (HCT 116) Human TMEM8B 1:2~1:4 Negative Online Inquiry
KO22226 TMEM8B Knockout cell line (HEK293) Human TMEM8B 1:3~1:6 Negative Online Inquiry
KO22227 TMEM8B Knockout cell line (A549) Human TMEM8B 1:3~1:4 Negative Online Inquiry

Background

TMEM8B Gene Knockout Cell Lines are genetically modified cell lines designed for the precise study of the TMEM8B gene's role in cellular processes. By utilizing CRISPR-Cas9 technology, these cell lines undergo targeted deletion of the TMEM8B gene, allowing researchers to investigate the specific functions and molecular pathways associated with its expression. The knockout model provides a unique opportunity to observe phenotypic changes and assess the biological consequences of TMEM8B loss, resulting in valuable insights into its potential implications in various diseases.

The mechanism behind the TMEM8B knockout involves the introduction of a guide RNA that directs the Cas9 nuclease to the TMEM8B locus. This precision enables the efficient disruption of the gene, allowing scientists to create a robust model for analyzing gene function and its interaction with other cellular components. By studying these knockout cell lines, researchers can elucidate the role of TMEM8B in processes such as cell signaling, membrane dynamics, and cellular stress responses.

Scientifically, the TMEM8B Gene Knockout Cell Lines hold significant importance in both basic and applied research. They can be utilized in studies related to neurodegenerative diseases, cancer biology, and immunology, where understanding the gene's function may lead to novel therapeutic strategies. Additionally, these platforms are valuable for screening compounds or exploring gene interactions, advancing the field of personalized medicine.

A notable advantage of our TMEM8B knockout cell lines is their high specificity and reproducibility compared to alternative models like RNA interference or transient knockdown methodologies. These cell lines provide a stable genetic background, which is crucial for longitudinal studies and multi-generational experiments. Our stringent quality assurance processes ensure that researchers receive cell lines that possess the desired knockout efficiency with minimal off-target effects.

For researchers, clinicians, and biopharmaceutical companies, the TMEM8B Gene Knockout Cell Lines offer a powerful tool for unlocking the mysteries of TMEM8B-related pathophysiology, enhancing research productivity, and enabling innovative discoveries. Our company brings years of expertise in genomic editing and cell line development, backing our products with a commitment to quality and customer support. We are dedicated to empowering the scientific community with cutting-edge biological products that facilitate impactful research and advancements in healthcare.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.