Gene: TMEM80
Official Full Name: transmembrane protein 80provided by HGNC
Gene Summary: Predicted to be involved in non-motile cilium assembly. Predicted to be located in cilium and membrane. Predicted to be active in ciliary transition zone. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13284 | TMEM80 Knockout cell line (HeLa) | Human | TMEM80 | 1:3~1:6 | Negative | Online Inquiry |
KO13285 | TMEM80 Knockout cell line (HCT 116) | Human | TMEM80 | 1:2~1:4 | Negative | Online Inquiry |
KO13286 | TMEM80 Knockout cell line (HEK293) | Human | TMEM80 | 1:3~1:6 | Negative | Online Inquiry |
KO13287 | TMEM80 Knockout cell line (A549) | Human | TMEM80 | 1:3~1:4 | Negative | Online Inquiry |
TMEM80 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to investigate the biological function of the TMEM80 gene. This innovative product enables researchers to elucidate the role of TMEM80 in various physiological and pathological processes, thereby advancing the understanding of its contributions to cellular signaling, development, and disease progression.
The key function of TMEM80 Gene Knockout Cell Lines lies in their ability to selectively silence the TMEM80 gene through targeted gene editing techniques, such as CRISPR/Cas9. This gene disruption allows for the examination of TMEM80's involvement in signaling pathways, cellular response to environmental stimuli, and its potential implications in disease states like cancer and neurodegeneration. By removing the TMEM80 gene’s influence, researchers gain insight into compensatory mechanisms that other pathways may employ and can track how the absence of this gene affects cellular behavior.
From a scientific standpoint, these cell lines provide indispensable tools for both basic research and translational studies. The knowledge generated can contribute to identifying novel therapeutic targets and biomarkers for diseases linked to TMEM80 dysfunction. In clinical settings, these insights could pave the way for potential interventions that leverage the modulation of TMEM80-related pathways, making them valuable assets in the field of personalized medicine.
Compared to alternative cell line models, TMEM80 Gene Knockout Cell Lines offer a specificity that is difficult to achieve with pharmacological inhibitors or siRNA approaches, which may not fully recapitulate the physiological relevance of a complete gene knockout. The precise and permanent alteration of the genome provides a stable platform for long-term studies and repeat experiments.
The value of TMEM80 Gene Knockout Cell Lines to researchers and clinicians cannot be overstated; by enabling a deeper understanding of gene function and its implications in health and disease, these cell lines can help drive significant advancements in biomedical research. At [Your Company Name], we are committed to providing exceptional quality biological products and expertise to empower scientists in their quest for knowledge and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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