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TMEM63C Knockout Cell Lines

Gene: TMEM63C

Official Full Name: transmembrane protein 63Cprovided by HGNC

Gene Summary: Enables calcium-activated cation channel activity. Involved in monoatomic cation transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Implicated in hereditary spastic paraplegia 87. Biomarker of focal segmental glomerulosclerosis. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13304 TMEM63C Knockout cell line (HeLa) Human TMEM63C 1:3~1:6 Negative Online Inquiry
KO13305 TMEM63C Knockout cell line (HCT 116) Human TMEM63C 1:2~1:4 Negative Online Inquiry
KO13306 TMEM63C Knockout cell line (HEK293) Human TMEM63C 1:3~1:6 Negative Online Inquiry

Background

TMEM63C Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the functional implications of the TMEM63C gene, which is implicated in various physiological and pathological processes. By utilizing CRISPR/Cas9 technology, our cell lines provide a powerful tool for researchers investigating the role of TMEM63C in cellular signaling, ion transport, and cellular responses to environmental stimuli.

The primary function of TMEM63C is associated with modulating intracellular calcium levels and facilitating cellular mechanosensitivity. Knockout of the TMEM63C gene provides researchers an opportunity to elucidate its role in various pathways, including those related to cell proliferation, differentiation, and apoptosis. The absence of this gene allows for the investigation of compensatory mechanisms that may emerge in its absence, providing insights into disease models where TMEM63C may be implicated, such as certain neurodegenerative disorders and cancers.

In both research and clinical settings, understanding the role of genes like TMEM63C is critical for the development of innovative therapeutic approaches. This gene knockout model enables high-throughput screening and functional assays that are pivotal in drug discovery and precision medicine.

One of the standout advantages of our TMEM63C Gene Knockout Cell Lines is the reliability and consistency in experimental results, allowing researchers to obtain reproducible data with confidence. Unlike other models that may exhibit variable expression levels of the gene, our knockout lines are validated for complete gene disruption, which enhances the robustness of biological studies and the translational potential of research findings.

For researchers and clinicians focused on advancing biomedical knowledge, these TMEM63C knockout models are invaluable. They provide not just a means to investigate fundamental biological questions, but also pave the way for novel therapeutic strategies that could emerge from a deeper understanding of TMEM63C's role in health and disease.

At [Your Company Name], we specialize in developing cutting-edge biological products that empower scientists and clinicians to push the boundaries of research. Our TMEM63C Gene Knockout Cell Lines exemplify our commitment to providing high-quality, innovative solutions tailored for the complexities of modern biological inquiry.

Please note that all services are for research use only. Not intended for any clinical use.

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