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TMEM52 Knockout Cell Lines

Gene: TMEM52

Official Full Name: transmembrane protein 52provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13311 TMEM52 Knockout cell line (HeLa) Human TMEM52 1:3~1:6 Negative Online Inquiry
KO13312 TMEM52 Knockout cell line (HCT 116) Human TMEM52 1:2~1:4 Negative Online Inquiry
KO13313 TMEM52 Knockout cell line (HEK293) Human TMEM52 1:3~1:6 Negative Online Inquiry

Background

TMEM52 Gene Knockout Cell Lines are genetically engineered model systems that facilitate the study of the TMEM52 gene's functional role in various biological processes. These cell lines have been developed using precise gene-editing techniques, such as CRISPR/Cas9, to create knockout variants that lack the expression of the TMEM52 gene. The absence of this gene allows researchers to interrogate its contributions to cellular mechanisms, disease pathology, and potential therapeutic targets, providing an invaluable tool for functional genomics.

The primary mechanism by which these cell lines operate is through the complete silencing of the TMEM52 gene, which encodes a membrane-associated protein implicated in various cellular functions, including cell migration, adhesion, and potentially immune responses. By utilizing these knockout lines, researchers can assess differences in cellular behavior compared to wild-type controls, shedding light on the gene's physiological relevance and its implications in health and disease, particularly cancer biology and neurodegenerative conditions.

The scientific importance of TMEM52 Gene Knockout Cell Lines lies in their ability to facilitate advanced research applications. They are critical in elucidating the role of TMEM52 in tumorigenesis, drug resistance, and other pathological states. Such insights can drive innovative therapies and diagnostic tools in clinical settings, thereby directly contributing to personalized medicine approaches.

What sets our TMEM52 Gene Knockout Cell Lines apart from alternatives is their rigorous validation, ensuring that the knockout status is confirmed and that the lines exhibit stable transgenic properties. This reliability enhances experimental reproducibility—a crucial factor for generating meaningful results. Furthermore, our product is accompanied by comprehensive support and technical documentation, aiding researchers in experimental design and application.

For researchers and clinicians, the value of TMEM52 Gene Knockout Cell Lines is profound. They enable the exploration of novel hypotheses and contribute to a deeper understanding of the mechanistic underpinnings of diseases, potentially paving the way for new therapeutic targets. Our company is dedicated to advancing scientific discovery and ensures that our products uphold the highest standards of quality and innovation in the realm of biological research. With a strong commitment to facilitating breakthroughs in life sciences, we provide top-tier products that help propel research and clinical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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