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TMEM50B Knockout Cell Lines

Gene: TMEM50B

Official Full Name: transmembrane protein 50Bprovided by HGNC

Gene Summary: Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00267 TMEM50B Knockout cell line (HeLa) Human TMEM50B 1:3~1:6 Negative Online Inquiry
KO38742 TMEM50B Knockout cell line (HCT 116) Human TMEM50B 1:2~1:4 Negative Online Inquiry
KO38743 TMEM50B Knockout cell line (HEK293) Human TMEM50B 1:3~1:6 Negative Online Inquiry
KO38744 TMEM50B Knockout cell line (A549) Human TMEM50B 1:3~1:4 Negative Online Inquiry

Background

TMEM50B Gene Knockout Cell Lines are genetically engineered cell lines that have undergone targeted deletion of the TMEM50B gene, providing a powerful tool for studying gene function and its implications in various biological processes. The TMEM50B gene is implicated in pathways related to endosomal trafficking and cellular response mechanisms, making its knockout an advantageous model for research focused on these areas.

The primary function of these knockout cell lines lies in their ability to elucidate the role of TMEM50B in protein localization, cellular signaling, and their potential impact on disease states, such as neurodegenerative disorders and cancer. By observing the phenotypic and molecular changes that occur with the absence of this specific gene, researchers can gain insights into the underlying mechanisms of diseases and identify potential therapeutic targets. This is achieved through advanced techniques such as transcriptomic and proteomic analyses, allowing for comprehensive profiling of cellular responses.

The scientific importance of TMEM50B Gene Knockout Cell Lines extends into both research and clinical settings, facilitating investigations into cellular physiology and pathology. These cell lines serve as valuable models for drug discovery, enabling screening of compounds that may modulate the functions disrupted by TMEM50B knockout, thereby contributing to the development of targeted therapies.

One of the key advantages of using TMEM50B Gene Knockout Cell Lines is their specificity; they provide a precise model to dissect the functions of the TMEM50B gene without the interference of compensatory mechanisms often seen in whole-organism studies. Compared to alternative models such as transient knockdown approaches or whole-organism studies, these knockout cell lines allow for reproducible results and a clearer understanding of the gene's role.

For researchers and clinicians striving for innovation in biomedical research, TMEM50B Gene Knockout Cell Lines offer significant value. They represent a robust system for detailed mechanistic studies and contribute to advancing the field of molecular biology and therapeutic development.

Leveraging years of expertise in genetic engineering and cell line development, our company is dedicated to providing high-quality biological products that empower scientific exploration and drive advancements in healthcare solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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