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TMEM45B Knockout Cell Lines

Gene: TMEM45B

Official Full Name: transmembrane protein 45Bprovided by HGNC

Gene Summary: Predicted to be involved in innate immune response. Predicted to be located in Golgi apparatus; endosome membrane; and lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30348 TMEM45B Knockout cell line (HeLa) Human TMEM45B 1:3~1:6 Negative Online Inquiry

Background

TMEM45B Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the TMEM45B gene, known for its roles in various cellular processes, including cellular signaling and interaction with the extracellular matrix. These knockout cell lines have been meticulously engineered to disrupt the TMEM45B gene, providing a powerful tool for researchers investigating gene function, protein interactions, and cellular responses in both physiological and pathological contexts.

The primary mechanism of action of these knockout lines lies in their ability to create a loss-of-function phenotype, allowing for the direct observation of changes in cellular behavior and gene expression associated with the absence of TMEM45B. This enables comprehensive studies into how the gene influences processes such as cellular migration, proliferation, and response to external stimuli. Additionally, researchers can utilize these models to explore mechanisms underlying diseases linked to aberrant TMEM45B function, including cancer progression and developmental disorders.

The scientific importance of TMEM45B Gene Knockout Cell Lines extends to both fundamental research and clinical applications, particularly in drug development and targeted therapies. By employing these models, researchers can identify potential therapeutic targets and elucidate disease mechanisms, ultimately contributing to more effective treatment strategies.

One of the standout advantages of our TMEM45B Gene Knockout Cell Lines is their robustness and reproducibility in experimental settings compared to other gene-editing approaches, such as CRISPR integration systems. Our lines are optimized for easy culturing and provide consistent results, ensuring that researchers can seamlessly integrate these models into their workflows.

For researchers, clinicians, and pharmaceutical companies, TMEM45B Gene Knockout Cell Lines represent a valuable investment in advancing understanding of gene functionality and its implications in disease; thereby driving innovation in research and therapeutic development. At [Your Company Name], we pride ourselves on our commitment to delivering high-quality biological products, backed by extensive expertise and support, making us your reliable partner in scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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