Gene: TMEM45A
Official Full Name: transmembrane protein 45Aprovided by HGNC
Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13318 | TMEM45A Knockout cell line (HeLa) | Human | TMEM45A | 1:3~1:6 | Negative | Online Inquiry |
KO13319 | TMEM45A Knockout cell line (HCT 116) | Human | TMEM45A | 1:2~1:4 | Negative | Online Inquiry |
KO13320 | TMEM45A Knockout cell line (HEK293) | Human | TMEM45A | 1:3~1:6 | Negative | Online Inquiry |
KO13321 | TMEM45A Knockout cell line (A549) | Human | TMEM45A | 1:3~1:4 | Negative | Online Inquiry |
TMEM45A Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to lack the expression of the Transmembrane Protein 45A (TMEM45A) gene. This innovative product serves as a powerful tool for researchers seeking to investigate the physiological and pathological roles of TMEM45A in various biological processes, including cellular signaling, differentiation, and disease progression. The creation of knockout cell lines utilizes CRISPR-Cas9 gene-editing technology, ensuring precise deletion of the target gene while minimizing off-target effects.
The primary mechanism of action for TMEM45A knockout cell lines lies in the absence of the TMEM45A protein, which is believed to influence cellular stress responses and tumorigenesis. By studying these knockout lines, researchers can gain invaluable insights into the impact of TMEM45A on tumor growth, metastasis, and responses to therapeutic interventions. This functionality is particularly relevant in oncology and regenerative medicine, where understanding gene function can inform treatment strategies and facilitate drug development.
In comparison to other genetic models, the TMEM45A knockout cell lines present distinct advantages, including a more straightforward approach to gene disruption, which reduces the time and resources spent in creating the cell lines. These knockout models allow for reproducible experimental results and a clearer understanding of gene function, which is crucial in both basic science and applied biomedical research.
The value of TMEM45A Gene Knockout Cell Lines extends beyond their scientific merits; they enable researchers and clinicians to explore novel therapeutic avenues and improve patient outcomes through detailed mechanistic studies. They are particularly beneficial for labs focused on cancer research, genetic disorders, and therapeutic interventions that target specific cellular pathways.
With a commitment to scientific excellence, our company specializes in providing high-quality genetic models, ensuring that our products, like the TMEM45A Gene Knockout Cell Lines, meet the highest standards of reliability and efficacy to empower pivotal research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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