Home / TMEM33 Knockout Cell Lines

TMEM33 Knockout Cell Lines

Gene: TMEM33

Official Full Name: transmembrane protein 33provided by HGNC

Gene Summary: Involved in positive regulation of endoplasmic reticulum unfolded protein response; regulation of endoplasmic reticulum tubular network organization; and response to endoplasmic reticulum stress. Located in endoplasmic reticulum membrane; melanosome; and nuclear envelope. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13340 TMEM33 Knockout cell line (HeLa) Human TMEM33 1:3~1:6 Negative Online Inquiry
KO13341 TMEM33 Knockout cell line (HCT 116) Human TMEM33 1:2~1:4 Negative Online Inquiry
KO13342 TMEM33 Knockout cell line (HEK293) Human TMEM33 1:3~1:6 Negative Online Inquiry
KO13343 TMEM33 Knockout cell line (A549) Human TMEM33 1:3~1:4 Negative Online Inquiry

Background

TMEM33 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the TMEM33 gene, a transmembrane protein implicated in several critical biological processes, including cellular signaling and viral pathogenesis. The knockout of the TMEM33 gene serves as a valuable tool for researchers aiming to dissect its role in various physiological conditions and diseases.

These cell lines function by providing a controlled environment for studying the absence of TMEM33 protein, allowing scientists to elucidate its biological pathways and effects on cellular behavior. By using CRISPR/Cas9 technology, the TMEM33 gene is selectively disrupted, ensuring precise and efficient editing. This results in a model that closely mimics disease states, facilitating the investigation of pathways relevant to immune responses, lipid metabolism, and potential oncogenic processes.

The scientific importance of these knockout cell lines extends beyond basic research; they are instrumental in drug discovery and development, aiding in the identification of novel therapeutic targets and the assessment of drug efficacy against conditions linked to TMEM33 dysfunction. Furthermore, they provide insights into viral interactions, particularly in understanding how viruses exploit TMEM33 pathways for entry and replication, thereby opening avenues for antiviral strategies.

Compared to other available models, TMEM33 Gene Knockout Cell Lines uniquely offer a direct approach to assessing gene function in real time, while minimizing off-target effects associated with older gene-editing methods. The specificity and reliability of these cell lines make them superior alternatives for researchers focused on gene function and therapeutic interventions.

For researchers and clinicians, the value of TMEM33 Gene Knockout Cell Lines lies in their ability to accelerate scientific discoveries and potentially lead to the development of innovative treatments. By utilizing this product, users gain access to cutting-edge technology that streamlines their research and enhances the understanding of critical biological mechanisms.

Our company prides itself on offering high-quality biological products backed by extensive research and development. With expertise in cutting-edge gene editing technologies and a commitment to supporting the scientific community, we are dedicated to providing products like the TMEM33 Gene Knockout Cell Lines that empower researchers to push the frontiers of biological discovery.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.