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TMEM260 Knockout Cell Lines

Gene: TMEM260

Official Full Name: transmembrane protein 260provided by HGNC

Gene Summary: Enables dolichyl-phosphate-mannose-protein mannosyltransferase activity. Involved in protein maturation. Is active in endoplasmic reticulum membrane. Implicated in T-cell non-Hodgkin lymphoma; non-Hodgkin lymphoma; and stomach cancer. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13174 TMEM260 Knockout cell line (HeLa) Human TMEM260 1:3~1:6 Negative Online Inquiry
KO13175 TMEM260 Knockout cell line (HCT 116) Human TMEM260 1:2~1:4 Negative Online Inquiry
KO13176 TMEM260 Knockout cell line (HEK293) Human TMEM260 1:3~1:6 Negative Online Inquiry
KO13177 TMEM260 Knockout cell line (A549) Human TMEM260 1:3~1:4 Negative Online Inquiry

Background

TMEM260 Gene Knockout Cell Lines are specifically engineered cell lines designed to facilitate the study of the TMEM260 gene's function and its associated biological pathways. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines exhibit a complete knockout of the TMEM260 gene, allowing researchers to observe the resultant phenotypic and molecular changes in a controlled environment. This approach provides a robust platform for investigating the gene's role in cellular processes, such as cell proliferation, differentiation, and response to stress.

The key function of the TMEM260 Gene Knockout Cell Lines lies in their ability to elucidate the biological implications of TMEM260 disruption. Researchers can employ these cell lines to assess alterations in signaling pathways, gene expression profiles, and metabolic activities that are impacted by the absence of TMEM260. This molecular insight is pivotal in advancing our understanding of various diseases where TMEM260 might play a critical role, thereby enhancing knowledge pertinent to both basic and applied research.

In addition to their research applications, these knockout cell lines hold substantial clinical importance. They can serve as models for evaluating therapeutic targets in cancer and other disorders linked to dysregulated TMEM260 function. By enabling the discovery of novel interventions, they support the translation of bench research findings into effective clinical applications.

What sets TMEM260 Gene Knockout Cell Lines apart from other gene-specific models is their precise editing and validation, ensuring reliability and reproducibility across experiments. The cell lines are also compatible with a variety of assays, including high-throughput screening, further enhancing their utility for researchers.

Researchers and clinicians stand to benefit significantly from incorporating TMEM260 Gene Knockout Cell Lines into their studies, as they represent a state-of-the-art tool for diving deep into gene function and potential therapeutic avenues. Our company specializes in providing high-quality biological products that enable innovative research, ensuring that our offerings meet the rigorous demands of scientific inquiry. By choosing our products, you gain access to reliable resources backed by our expertise and commitment to advancing scientific knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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