Gene: TMEM254
Official Full Name: transmembrane protein 254provided by HGNC
Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26155 | TMEM254 Knockout cell line (HeLa) | Human | TMEM254 | 1:3~1:6 | Negative | Online Inquiry |
KO26156 | TMEM254 Knockout cell line (HCT 116) | Human | TMEM254 | 1:2~1:4 | Negative | Online Inquiry |
KO26157 | TMEM254 Knockout cell line (HEK293) | Human | TMEM254 | 1:3~1:6 | Negative | Online Inquiry |
KO26158 | TMEM254 Knockout cell line (A549) | Human | TMEM254 | 1:3~1:4 | Negative | Online Inquiry |
TMEM254 Gene Knockout Cell Lines are specialized cellular models engineered to lack the TMEM254 gene, a member of the transmembrane protein family associated with various cellular processes, including ion transport and immune responses. By utilizing CRISPR-Cas9 technology, these knockout cell lines provide researchers with precise tools to elucidate the gene's biological functions, offering insights into its role in cellular signaling and disease mechanisms.
The primary function of TMEM254 knockout cell lines is to serve as a platform for functional genomics, allowing scientists to study the consequences of the gene's absence on cell behavior, such as proliferation, differentiation, and response to stimuli. Mechanistically, the cell lines enable researchers to investigate alterations in downstream signaling pathways, providing a clearer picture of how TMEM254 impacts key biological processes, particularly in immune regulation and potential oncogenic pathways.
The scientific importance of these cell lines lies in their applications in both fundamental research and clinical settings. They can facilitate drug discovery by identifying potential therapeutic targets and evaluating drug efficacy in a controlled environment. Moreover, as researchers explore the implications of TMEM254 in disease contexts, these knockout models can contribute to understanding autoimmune diseases and cancers, paving the way for innovative treatment strategies.
Compared to traditional cell lines or gene silencing methods, TMEM254 knockout cell lines offer distinct advantages, including the permanence of gene deletion and the ability to examine long-term effects without transient variability. Their robustness and reliability make them an ideal choice for experimental designs requiring high reproducibility.
For researchers and clinicians focused on advancing knowledge in molecular biology and therapeutics, these knockout cell lines present a valuable asset. They not only enhance the depth of investigations but also improve translational potential in clinical applications. Our company prides itself on its commitment to providing high-quality biological products, backed by a team of experts dedicated to supporting scientific inquiry and innovation in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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