Gene: TMEM248
Official Full Name: transmembrane protein 248provided by HGNC
Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20169 | TMEM248 Knockout cell line (HeLa) | Human | TMEM248 | 1:3~1:6 | Negative | Online Inquiry |
KO20170 | TMEM248 Knockout cell line (HCT 116) | Human | TMEM248 | 1:2~1:4 | Negative | Online Inquiry |
KO20171 | TMEM248 Knockout cell line (HEK293) | Human | TMEM248 | 1:3~1:6 | Negative | Online Inquiry |
KO20172 | TMEM248 Knockout cell line (A549) | Human | TMEM248 | 1:3~1:4 | Negative | Online Inquiry |
TMEM248 Gene Knockout Cell Lines are specialized cellular models designed to investigate the biological roles of the TMEM248 gene, which is implicated in various cellular processes, including growth regulation and cell signaling. These cell lines are generated through advanced CRISPR-Cas9 gene editing technology, enabling the specific ablation of the TMEM248 gene to study its function in a controlled environment. By knocking out this gene, researchers can dissect its contribution to various physiological and pathological processes, providing insights into its role in diseases such as cancer and metabolic disorders.
The primary function of TMEM248 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function and interactions. Researchers can utilize these models to observe the effects of gene disruption on cellular behaviors such as proliferation, differentiation, and apoptosis. Mechanistically, the absence of TMEM248 is expected to reveal critical pathways and molecular mechanisms that are altered in its absence, thus serving as a valuable tool for understanding disease mechanisms and identifying potential therapeutic targets.
Scientific importance stems from the application of these knockout models in both basic and applied research realms. They provide a unique opportunity for drug discovery, where the effect of potential therapeutics on TMEM248-deficient cells can be assessed, contributing to the development of targeted therapies. Furthermore, these models support essential validation studies in genetic research, enhancing our understanding of gene function in both normal and diseased states.
Compared to alternative gene manipulation strategies, such as overexpression systems, TMEM248 Gene Knockout Cell Lines offer a more precise approach to scrutinizing gene loss and its biological consequences. Researchers benefit from this specificity, which minimizes confounding variables associated with non-specific gene expression enhancements. Additionally, the robust performance and reproducibility of these cell lines position them as unparalleled resources in genetic research.
In summary, TMEM248 Gene Knockout Cell Lines are invaluable to researchers and clinicians aiming to delve into the complexities of gene function and its implications in health and disease. Our company has a proven track record of providing high-quality biological products, reflecting our commitment to supporting innovative research with precise, reliable tools. As a leader in the field, we enable our clients to investigate the frontiers of biology with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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