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TMEM238L Knockout Cell Lines

Gene: TMEM238L

Official Full Name: transmembrane protein 238 likeprovided by HGNC

Gene Summary: Involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13187 TMEM238L Knockout cell line (HeLa) Human TMEM238L 1:3~1:6 Negative Online Inquiry
KO13188 TMEM238L Knockout cell line (HCT 116) Human TMEM238L 1:2~1:4 Negative Online Inquiry
KO13189 TMEM238L Knockout cell line (A549) Human TMEM238L 1:3~1:4 Negative Online Inquiry

Background

TMEM238L Gene Knockout Cell Lines are genetically engineered cellular models designed to study the functions and implications of the TMEM238L gene, which is known to play a critical role in various physiological processes, including cellular signaling and membrane dynamics. By employing CRISPR/Cas9 technology, these cell lines provide a precise and effective method for generating knockout models devoid of TMEM238L expression, enabling researchers to investigate the gene’s contributions to cellular behavior and disease mechanisms.

The key function of the TMEM238L knockout cell lines lies in their ability to facilitate in-depth functional analyses. By knocking out the TMEM238L gene, researchers can explore its role in processes such as cell proliferation, differentiation, and response to external stimuli. This provides a unique opportunity to uncover potential pathways that may be disrupted in various diseases, including but not limited to cancer and metabolic disorders. The absence of TMEM238L expression offers a powerful tool for deciphering its biological significance and may pave the way for identifying new therapeutic targets.

Scientific importance and applications of these knockout cell lines extend to both research and clinical settings. They are invaluable for elucidating mechanisms underlying gene function, validating drug targets, and screening for novel compounds. Furthermore, they can serve as a platform for developing gene therapy techniques, thus aligning with the growing emphasis on personalized medicine approaches.

What sets TMEM238L Gene Knockout Cell Lines apart from alternative models is their unparalleled specificity and reliability. Traditional knockdown methods often employ transient transfection techniques that can yield inconsistent results and may not completely ablate gene function. In contrast, our knockout cell lines guarantee a stable and complete lack of TMEM238L expression, ensuring reproducibility and valid experimental outcomes.

For researchers and clinicians seeking to expand their understanding of gene function in health and disease, our TMEM238L Gene Knockout Cell Lines represent an essential resource. They enable a deeper exploration of complex biological systems and may lead to significant discoveries in the field of molecular biology and translational medicine.

Our company specializes in providing high-quality, innovative biological products backed by extensive research and expertise. With a commitment to advancing scientific knowledge, we offer a diverse portfolio of gene knockout models tailored to support the research community in achieving their scientific goals.

Please note that all services are for research use only. Not intended for any clinical use.

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