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TMEM220 Knockout Cell Lines

Gene: TMEM220

Official Full Name: transmembrane protein 220provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13206 TMEM220 Knockout cell line (HEK293) Human TMEM220 1:3~1:6 Negative Online Inquiry
KO13207 TMEM220 Knockout cell line (A549) Human TMEM220 1:3~1:4 Negative Online Inquiry

Background

TMEM220 Gene Knockout Cell Lines represent a significant advancement in cellular biology, providing robust models for studying the functional implications of the TMEM220 gene in various biological processes. These cell lines have been engineered through CRISPR/Cas9 technology to introduce targeted deletions in the TMEM220 gene, leading to the complete loss of its expression. This precise gene knockout approach allows researchers to elucidate the role of TMEM220 in cellular mechanisms such as apoptosis, cell proliferation, and signal transduction pathways.

The key mechanism underpinning the utility of these cell lines lies in the ability to create a controlled environment for examining gene function and its implications in disease models. As TMEM220 is implicated in neurobiological functions and certain pathologies, including neurodegenerative diseases, using these knockout lines facilitates the exploration of its contribution to disease phenotypes in a highly reproducible manner. Consequently, they serve as a valuable asset for drug discovery, as they enable the identification of potential therapeutic targets and the assessment of drug efficacy in a genetically consistent background.

In comparison to other gene knockout models, TMEM220 Gene Knockout Cell Lines offer distinct advantages such as high efficiency and specificity in gene editing, leading to clearer results in functional assays. Additionally, the availability of these lines as ready-to-use products saves researchers considerable time and resources associated with developing their knockout models from scratch.

This product is particularly valuable for academic and industrial researchers focused on molecular biology, pharmacology, and genetics, as it opens avenues for innovative studies that may lead to breakthroughs in understanding disease mechanisms and therapy development. With TMEM220 Gene Knockout Cell Lines, researchers can confidently explore the complexities of cellular pathways with a model that accurately reflects the biological context.

Our company specializes in providing cutting-edge biological products and technologies rooted in rigorous scientific validation, ensuring that researchers and clinicians have access to the tools necessary for advancing their work in cellular biology and related disciplines.

Please note that all services are for research use only. Not intended for any clinical use.

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