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TMEM219 Knockout Cell Lines

Gene: TMEM219

Official Full Name: transmembrane protein 219provided by HGNC

Gene Summary: Predicted to be involved in apoptotic process. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28046 TMEM219 Knockout cell line (HeLa) Human TMEM219 1:3~1:6 Negative Online Inquiry
KO28047 TMEM219 Knockout cell line (HCT 116) Human TMEM219 1:2~1:4 Negative Online Inquiry
KO28048 TMEM219 Knockout cell line (HEK293) Human TMEM219 1:3~1:6 Negative Online Inquiry
KO28049 TMEM219 Knockout cell line (A549) Human TMEM219 1:3~1:4 Negative Online Inquiry

Background

TMEM219 Gene Knockout Cell Lines represent an innovative tool for researchers engaged in the exploration of cellular mechanisms and disease modeling. These cell lines are specifically engineered to disrupt the TMEM219 gene, an essential component implicated in various cellular processes, including endosomal trafficking and immune response modulation. The gene knockout is achieved through advanced CRISPR-Cas9 technology, ensuring precise genomic editing and the establishment of a reliable and reproducible cellular model.

The primary function of TMEM219 Gene Knockout Cell Lines is to facilitate the study of gene function and its impact on cellular behavior under different physiological conditions. By examining the cellular pathways affected by the absence of TMEM219, researchers can unravel its role in relevant biological processes, such as cell signaling, inflammation, and potential oncogenic pathways. This functionality underscores the lines’ potential applications in drug discovery and the development of targeted therapeutics.

In comparison to alternative models, such as wild-type or overexpression systems, TMEM219 Gene Knockout Cell Lines offer a unique advantage by providing a loss-of-function context. This feature allows for a more nuanced understanding of gene interactions and the development of strategies aimed at modulating pathological states in clinical contexts.

The value of this product extends beyond basic research; it paves the way for translational studies in areas such as cancer biology, autoimmunity, and infectious diseases. Clinicians and researchers alike will find TMEM219 Gene Knockout Cell Lines indispensable for their experimental designs, enabling them to draw clearer connections between genetic alterations and disease phenotypes.

As a leader in genetic engineering products, our company is committed to providing high-quality, reliable biotechnology solutions that empower researchers to advance their scientific inquiries and therapeutic discoveries. Our expertise in developing precision cell lines ensures that you will receive a product that meets the highest standards of performance and reliability.

Please note that all services are for research use only. Not intended for any clinical use.

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