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TMEM198 Knockout Cell Lines

Gene: TMEM198

Official Full Name: transmembrane protein 198provided by HGNC

Gene Summary: Involved in positive regulation of canonical Wnt signaling pathway. Located in cytoplasmic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26608 TMEM198 Knockout cell line (HeLa) Human TMEM198 1:3~1:6 Negative Online Inquiry
KO26609 TMEM198 Knockout cell line (HCT 116) Human TMEM198 1:2~1:4 Negative Online Inquiry
KO26610 TMEM198 Knockout cell line (HEK293) Human TMEM198 1:3~1:6 Negative Online Inquiry

Background

TMEM198 Gene Knockout Cell Lines represent a cutting-edge product designed for researchers investigating the functional roles of the TMEM198 gene in cellular processes. These genetically modified cell lines have been meticulously engineered using CRISPR/Cas9 technology to create precise deletions in the TMEM198 gene, allowing for comprehensive studies into its involvement in various biological pathways, including cellular stress responses, membrane trafficking, and cancer progression.

The primary mechanism of action for these knockout cell lines lies in the loss of TMEM198 expression, effectively producing a model system that facilitates the examination of downstream effects on cellular functions. By comparing these knockout lines to their wild-type counterparts, researchers can elucidate the physiological and pathological implications of TMEM198, thereby contributing to a deeper understanding of its role in health and disease.

The scientific importance of the TMEM198 Gene Knockout Cell Lines extends beyond basic research; they can be invaluable in translational medicine, particularly in the development of targeted therapies for diseases involving aberrant TMEM198 function. Their application in drug discovery, molecular pathology, and cancer research equips scientists with the tools necessary to develop innovative strategies that might translate into improved therapeutic approaches.

Compared to conventional genetic models, TMEM198 Gene Knockout Cell Lines offer the distinct advantage of high specificity and reduced off-target effects, which are critical in obtaining reliable and reproducible data. Moreover, these cell lines are ready-to-use, saving valuable time in experimental design and implementation.

For researchers and clinicians aiming to explore the intricate functions of the TMEM198 gene, our product provides a unique, reliable, and versatile tool that can significantly enhance the depth and quality of their investigations. Our company, with extensive expertise in biotechnological innovations, is committed to delivering products that empower the scientific community to push the boundaries of knowledge and innovation in biology.

Please note that all services are for research use only. Not intended for any clinical use.

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