Gene: TMEM177
Official Full Name: transmembrane protein 177provided by HGNC
Gene Summary: Involved in mitochondrial respiratory chain complex II assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25896 | TMEM177 Knockout cell line (HeLa) | Human | TMEM177 | 1:3~1:6 | Negative | Online Inquiry |
KO25897 | TMEM177 Knockout cell line (HCT 116) | Human | TMEM177 | 1:2~1:4 | Negative | Online Inquiry |
KO25898 | TMEM177 Knockout cell line (HEK293) | Human | TMEM177 | 1:3~1:6 | Negative | Online Inquiry |
KO25899 | TMEM177 Knockout cell line (A549) | Human | TMEM177 | 1:3~1:4 | Negative | Online Inquiry |
TMEM177 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed to facilitate the study of the TMEM177 gene's function and its implications in various biological processes. These knockout cell lines have been genetically modified to disrupt the expression of the TMEM177 gene, allowing researchers to investigate the gene's biological role and its potential impact on cellular pathways. By utilizing CRISPR/Cas9 or similar genome editing technologies, these cell lines provide a reliable model for analyzing changes in cellular behavior, signaling, and metabolic processes associated with the loss of TMEM177 function.
The key functionality of TMEM177 Gene Knockout Cell Lines lies in their ability to mimic disease conditions, thereby enabling scientists to explore the underlying mechanisms of pathogenesis more effectively. Through phenotypic analyses, researchers can assess alterations in cell proliferation, differentiation, apoptosis, and immune response, providing valuable insights that may lead to novel therapeutic targets. The use of these cell lines in research settings enhances our understanding of TMEM177's role in various diseases, such as cancer and metabolic disorders.
In clinical and research applications, the unique advantage of TMEM177 Gene Knockout Cell Lines over traditional models is their specificity and precision. They offer researchers a streamlined approach to dissect the complex biological functions of genes in question, reducing the time and resources spent on developing and validating alternate models. Compared to wild-type cell lines, knockout lines can provide clearer insights into gene function and facilitate high-throughput screening processes for potential drug candidates.
Researchers and clinicians value these cell lines not only for their methodological rigor but also for their potential to expedite the research process. With the growing focus on personalized medicine, understanding the genetic basis of diseases is paramount; thus, the availability of TMEM177 Gene Knockout Cell Lines can be a vital asset in advancing both basic and translational research initiatives.
Our company prides itself on delivering high-quality biological products that empower scientific discovery and innovation. With a dedicated team of molecular biologists and genetic engineers, we are committed to helping researchers unlock the secrets of gene function efficiently and effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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