Gene: TMEM164
Official Full Name: transmembrane protein 164provided by HGNC
Gene Summary: Involved in positive regulation of ferroptosis. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25121 | TMEM164 Knockout cell line (HeLa) | Human | TMEM164 | 1:3~1:6 | Negative | Online Inquiry |
KO25122 | TMEM164 Knockout cell line (HCT 116) | Human | TMEM164 | 1:2~1:4 | Negative | Online Inquiry |
KO25123 | TMEM164 Knockout cell line (HEK293) | Human | TMEM164 | 1:3~1:6 | Negative | Online Inquiry |
KO25124 | TMEM164 Knockout cell line (A549) | Human | TMEM164 | 1:3~1:4 | Negative | Online Inquiry |
TMEM164 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the function and pathology associated with the TMEM164 gene. This gene has been linked to critical biological processes, including cellular signaling, immune response, and potential implications in various diseases. The creation of these knockout cell lines allows researchers to elucidate the gene's role by completely removing its expression, thereby enabling a deeper understanding of TMEM164's contributions to cellular homeostasis and disease mechanisms.
The key mechanism behind the TMEM164 Gene Knockout Cell Lines is the CRISPR-Cas9 technology employed during their development. This sophisticated method facilitates precise genetic edits, ensuring that the TMEM164 gene is fully inactivated. Researchers can utilize these cell lines to observe any resultant phenotypic changes, ranging from alterations in cell proliferation, differentiation, and apoptosis to shifts in metabolic pathways. Such functional assays are pivotal for uncovering the molecular pathways that may be disrupted in pathophysiological states.
The scientific relevance of TMEM164 Gene Knockout Cell Lines cannot be overstated, as they offer invaluable insights into the gene's role in diseases such as immune disorders and cancers, making them instrumental in both research and potential therapeutic applications. Their use in innovative gene targeting and drug discovery platforms places them at the forefront of genetic research, contributing to the development of targeted therapies.
Compared to conventional methods, such as stable transfection or RNA interference, these knockout cell lines present unparalleled specificity and efficiency. With the ability to completely abrogate gene function, they eliminate the caveats associated with residual gene activity often observed with alternative techniques, thereby providing cleaner experimental outcomes.
Researchers and clinicians seeking to delve into the functional dynamics of TMEM164 will find exceptional value in these cell lines. Their well-characterized nature, along with the robust experimental data supporting their use, makes them an indispensable tool for cutting-edge research.
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Please note that all services are for research use only. Not intended for any clinical use.
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