Gene: TMEM161B
Official Full Name: transmembrane protein 161Bprovided by HGNC
Gene Summary: Predicted to enable nucleic acid binding activity. Predicted to be involved in regulation of cardiac muscle cell action potential and regulation of heart rate. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00418 | TMEM161B Knockout cell line (HeLa) | Human | TMEM161B | 1:3~1:6 | Negative | Online Inquiry |
KO21531 | TMEM161B Knockout cell line (HCT 116) | Human | TMEM161B | 1:2~1:4 | Negative | Online Inquiry |
KO21532 | TMEM161B Knockout cell line (HEK293) | Human | TMEM161B | 1:3~1:6 | Negative | Online Inquiry |
KO21533 | TMEM161B Knockout cell line (A549) | Human | TMEM161B | 1:3~1:4 | Negative | Online Inquiry |
TMEM161B Gene Knockout Cell Lines are advanced cellular models specifically engineered to facilitate the study of the TMEM161B gene's role in various biological processes. This innovative product uses CRISPR-Cas9 technology to achieve precise gene disruption, thereby providing a platform for researchers to investigate the resulting phenotypic changes and molecular pathways influenced by TMEM161B.
The primary function of TMEM161B is believed to be involved in cellular ion transport and synaptic function, making it particularly relevant in neuroscience and developmental biology. By utilizing these knockout cell lines, researchers can explore the consequences of TMEM161B absence on neuronal activity, synaptic plasticity, and overall cellular health. The mechanism revolves around the analysis of signaling pathways and functional assays that assess alterations in neurotransmitter release and intracellular calcium levels, leading to a deeper understanding of neurotransmission-related disorders.
From a scientific standpoint, TMEM161B is implicated in various neurodegenerative diseases and conditions like autism spectrum disorders. Therefore, these cell lines have significant applications in both research and clinical settings, providing a robust model for drug screening, gene therapy development, and biomarker discovery.
What sets TMEM161B Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, derived from cutting-edge gene editing techniques. Unlike other knockout models, our product includes extensive validation, ensuring the absence of off-target effects, allowing researchers to confidently attribute observed phenotypes directly to TMEM161B.
These cell lines are invaluable to neuroscientists and pharmacologists who seek to explore the molecular underpinnings of diseases at a cellular level. Our commitment to quality and innovation underlines our expertise in providing top-tier biological products that empower researchers to achieve significant advancements in their studies. With a strong focus on customer support and detailed product information, we stand ready to assist in accelerating your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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