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TMEM151A Knockout Cell Lines

Gene: TMEM151A

Official Full Name: transmembrane protein 151Aprovided by HGNC

Gene Summary: Located in endoplasmic reticulum and membrane. Implicated in episodic kinesigenic dyskinesia 3. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21041 TMEM151A Knockout cell line (HCT 116) Human TMEM151A 1:2~1:4 Negative Online Inquiry

Background

TMEM151A Gene Knockout Cell Lines are revolutionary biological products designed to facilitate in-depth research on the TMEM151A gene, which plays a critical role in cellular mechanisms, particularly in the field of immunology and cancer biology. These cell lines have been meticulously engineered to have a complete knockout of the TMEM151A gene, allowing for precise studies into its biological functions and contributions to various pathophysiological conditions.

The key mechanism of the TMEM151A gene involves its regulation of immune responses and cellular signaling pathways. By creating a knockout model, researchers can investigate the specific roles of TMEM151A in processes such as cell adhesion, migration, and immune cell activation. This understanding is crucial, as aberrations in these processes can lead to autoimmune diseases and cancer. The use of these cell lines enables scientists to dissect the underlying molecular mechanisms and therapeutic potential that TMEM151A may offer.

The scientific importance of these knockout cell lines is multifaceted; they serve as valuable tools in both fundamental research settings and translational applications. For instance, the technology can be pivotal in drug discovery and testing, where the effects of potential therapeutic agents on TMEM151A-deficient cells can be evaluated. Moreover, these models can provide insights into the gene's role in tumorigenesis, enabling a better understanding of the behavior of cancerous cells.

Compared to alternative models, such as wild-type cell lines or other knockout systems, TMEM151A Gene Knockout Cell Lines offer unparalleled specificity and reproducibility. Their generation follows rigorous genetic engineering guidelines to ensure that the cell lines exhibit stable, consistent knockout characteristics, thereby enhancing the reliability of experimental outcomes.

For researchers and clinicians, these cell lines present immense value by streamlining experimental workflows and reducing the complexity associated with gene manipulation. By utilizing these advanced models, professionals can rapidly advance their studies into immune signaling and cancer biology, ultimately paving the way for innovative therapeutic solutions.

At our company, we pride ourselves on our leading-edge expertise in genetic engineering and cell line development. Our products, including the TMEM151A Gene Knockout Cell Lines, are backed by extensive research and are designed to meet the highest standards of scientific rigor, ensuring that our clients have the best tools available for their investigative needs.

Please note that all services are for research use only. Not intended for any clinical use.

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