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TMEM132E Knockout Cell Lines

Gene: TMEM132E

Official Full Name: transmembrane protein 132Eprovided by HGNC

Gene Summary: Involved in posterior lateral line neuromast hair cell development. Predicted to be located in cell body. Implicated in autosomal recessive nonsyndromic deafness 99. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27943 TMEM132E Knockout cell line (HEK293) Human TMEM132E 1:3~1:6 Negative Online Inquiry

Background

TMEM132E Gene Knockout Cell Lines are specialized model systems engineered to have the TMEM132E gene completely inactivated, allowing researchers to investigate the biological role of this gene in various cellular processes. TMEM132E, a member of the transmembrane protein family, has been implicated in several pathways, including those related to stress response, cellular signaling, and immune modulation. By utilizing knockout cell lines, researchers can discern the specific functions and contributions of TMEM132E in a controlled setting, facilitating the study of cellular mechanisms in health and disease.

The primary function of these cell lines is to provide a platform for loss-of-function studies, enabling the analysis of gene expression, protein interactions, and downstream signaling pathways that are affected by the absence of TMEM132E. This mechanistic understanding is crucial for elucidating the gene's role in pathologies such as autoimmune diseases, neurological disorders, and cancer, contributing to targeted therapeutic developments.

The scientific importance of TMEM132E Gene Knockout Cell Lines lies in their versatility in research and clinical applications. They can serve as valuable tools in drug discovery, genetic research, and the exploration of potential gene therapy approaches. By offering insights into the gene's function, these cell lines can assist in identifying biomarkers and therapeutic targets, thereby enhancing the development of precision medicine strategies.

Compared to alternative cell line models, the TMEM132E knockout lines offer a high degree of specificity and sensitivity, allowing for precise measurements of gene activity and cellular responses without the confounding effects of the gene in question. Additionally, they are pre-validated for consistent performance, facilitating reproducibility across experiments.

For researchers and clinicians seeking to advance their understanding of complex biological systems and disease mechanisms, TMEM132E Gene Knockout Cell Lines represent a critical resource that empowers innovative research and therapeutic discovery. Our company prides itself on its expertise in genetic engineering and cell line development, ensuring that our products meet the highest standards of scientific rigor and reliability, equipping our users with the necessary tools to make groundbreaking discoveries in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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