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TMEM131L Knockout Cell Lines

Gene: TMEM131L

Official Full Name: transmembrane 131 likeprovided by HGNC

Gene Summary: Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of immature T cell proliferation in thymus. Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29638 TMEM131L Knockout cell line (HeLa) Human TMEM131L 1:3~1:6 Negative Online Inquiry
KO29639 TMEM131L Knockout cell line (HCT 116) Human TMEM131L 1:2~1:4 Negative Online Inquiry
KO29640 TMEM131L Knockout cell line (HEK293) Human TMEM131L 1:3~1:6 Negative Online Inquiry
KO29641 TMEM131L Knockout cell line (A549) Human TMEM131L 1:3~1:4 Negative Online Inquiry

Background

TMEM131L Gene Knockout Cell Lines are a revolutionary tool designed for researchers studying the function of the TMEM131L gene, which has been implicated in various cellular processes and disease mechanisms. Through the targeted disruption of this gene, our cell lines facilitate in-depth investigations into the biological pathways that TMEM131L influences, thereby providing a valuable resource for the study of gene function and regulation.

The primary mechanism of our TMEM131L Gene Knockout Cell Lines is based on CRISPR/Cas9 technology, which enables precise editing of the genome. By introducing specific double-strand breaks at the target site within the TMEM131L gene, our cell lines undergo non-homologous end joining repair, leading to the creation of insertions or deletions that effectively disrupt gene expression. This knockout allows researchers to observe phenotypic changes, elucidate molecular pathways, and understand the broader implications of TMEM131L in health and disease.

From a scientific standpoint, these cell lines are particularly significant as they open avenues for research into novel therapeutic targets for conditions such as cancer and neurodegenerative disorders where TMEM131L has a role. Furthermore, they serve as a platform to test hypotheses regarding gene functions in cellular processes such as apoptosis, proliferation, and signal transduction.

Compared to traditional knockout models, our TMEM131L Gene Knockout Cell Lines offer unparalleled specificity and efficiency, reducing the time and resources required for gene editing. Additionally, they provide a ready-to-use resource that accelerates the pace of research and allows investigators to obtain reproducible results effectively.

For researchers and clinicians focused on gene function characterization or therapeutic development, our TMEM131L Gene Knockout Cell Lines are a vital addition to their toolkit. With our robust support and expertise in genetic engineering, our company is committed to delivering high-quality biological products that empower innovative research across the life sciences spectrum.

Please note that all services are for research use only. Not intended for any clinical use.

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