Gene: TMEM126A
Official Full Name: transmembrane protein 126Aprovided by HGNC
Gene Summary: The protein encoded by this gene is a mitochondrial membrane protein of unknown function. Defects in this gene are a cause of optic atrophy type 7 (OPA7). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25081 | TMEM126A Knockout cell line (HeLa) | Human | TMEM126A | 1:3~1:6 | Negative | Online Inquiry |
KO25082 | TMEM126A Knockout cell line (HCT 116) | Human | TMEM126A | 1:2~1:4 | Negative | Online Inquiry |
KO25083 | TMEM126A Knockout cell line (HEK293) | Human | TMEM126A | 1:3~1:6 | Negative | Online Inquiry |
KO25084 | TMEM126A Knockout cell line (A549) | Human | TMEM126A | 1:3~1:4 | Negative | Online Inquiry |
TMEM126A Gene Knockout Cell Lines are advanced cellular models designed to facilitate the study of the TMEM126A gene's function and its implications in various biological processes and diseases. By utilizing CRISPR/Cas9 technology, these cell lines have been meticulously engineered to lack the endogenous TMEM126A gene, allowing researchers to investigate the phenotypic consequences of gene knockout in a controlled environment. This model is pivotal for understanding how alterations in the TMEM126A gene may affect cellular processes such as mitochondrial function, signaling pathways, and metabolic regulation.
The TMEM126A gene is implicated in several important cellular functions, particularly related to mitochondrial biogenesis and dynamics. By studying knockout cell lines, researchers can elucidate the mechanisms by which TMEM126A influences cellular homeostasis and its potential role in metabolic disorders and neurodegenerative diseases. This model also opens avenues for drug screening and the identification of novel therapeutic targets, making it a crucial tool in both research and development.
One of the significant advantages of TMEM126A Gene Knockout Cell Lines is the specificity and efficiency of CRISPR technology, which allows for precise gene editing without off-target effects commonly associated with older methods. Additionally, the availability of these knockout lines supports reproducibility and consistency in experimental procedures, essential for validating scientific findings across multiple studies.
These cell lines are valuable assets for researchers and clinicians who aim to dissect the pathological functions of TMEM126A, explore its role in disease mechanisms, or develop targeted therapies. Leveraging these knockout models contributes to a deeper understanding of cellular biology and presents opportunities for breakthroughs in biomedical research.
Our company specializes in the development of high-quality genetic tools for the scientific community, backed by rigorous validation and a commitment to advancing research. By choosing TMEM126A Gene Knockout Cell Lines, you align with a product that not only enhances your research capabilities but also stands at the forefront of genetic exploration and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.