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TMEM115 Knockout Cell Lines

Gene: TMEM115

Official Full Name: transmembrane protein 115provided by HGNC

Gene Summary: Enables identical protein binding activity. Involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Located in Golgi cisterna membrane; Golgi transport complex; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31258 TMEM115 Knockout cell line (HeLa) Human TMEM115 1:3~1:6 Negative Online Inquiry
KO31259 TMEM115 Knockout cell line (HCT 116) Human TMEM115 1:2~1:4 Negative Online Inquiry
KO31260 TMEM115 Knockout cell line (HEK293) Human TMEM115 1:3~1:6 Negative Online Inquiry
KO31261 TMEM115 Knockout cell line (A549) Human TMEM115 1:3~1:4 Negative Online Inquiry

Background

TMEM115 Gene Knockout Cell Lines are specialized cellular models that have undergone precise genomic editing to entirely ablate the expression of the TMEM115 gene. This innovative tool provides researchers a unique opportunity to study the role of TMEM115, a protein implicated in various physiological processes, including cellular trafficking and membrane dynamics. The knockout mechanism is achieved through CRISPR-Cas9 technology, allowing for high specificity in gene targeting, resulting in a near-complete loss of function for this gene.

The primary function of TMEM115 is hypothesized to be critical for maintaining cellular homeostasis and regulating vesicle membranes within the endosomal and secretory pathways. By utilizing these knockout cell lines, researchers can gain insights into the underlying mechanisms by which TMEM115 influences cellular functions, facilitating the exploration of its potential involvement in disease pathology, including neurodegenerative disorders and cancer metastasis.

In both research and clinical applications, TMEM115 Gene Knockout Cell Lines present significant advantages over conventional models. Their high degree of specificity eliminates off-target effects commonly associated with less refined knockout strategies, ensuring more accurate experimental outcomes. This specificity will provide clearer data for researchers examining gene function, therapeutic targets, and potential biomarkers associated with cellular dysfunction.

What sets our TMEM115 Gene Knockout Cell Lines apart is their comprehensively validated performance in diverse applications, ranging from drug screening and pathway analysis to metabolic studies. The ability to elucidate the biological role of TMEM115 in various cellular contexts can lead to groundbreaking discoveries, enhancing our understanding of cellular biology and potential therapeutic interventions.

Our company is committed to providing state-of-the-art biological products, leveraging cutting-edge genomic technologies and a team of dedicated experts. By choosing our TMEM115 Gene Knockout Cell Lines, researchers and clinicians invest in a reliable tool that underscores their commitment to scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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