Gene: TMEM109
Official Full Name: transmembrane protein 109provided by HGNC
Gene Summary: Predicted to enable voltage-gated monoatomic cation channel activity. Acts upstream of or within cellular response to gamma radiation and negative regulation of programmed cell death. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13262 | TMEM109 Knockout cell line (HeLa) | Human | TMEM109 | 1:3~1:6 | Negative | Online Inquiry |
KO13263 | TMEM109 Knockout cell line (HCT 116) | Human | TMEM109 | 1:2~1:4 | Negative | Online Inquiry |
KO13264 | TMEM109 Knockout cell line (HEK293) | Human | TMEM109 | 1:3~1:6 | Negative | Online Inquiry |
KO13265 | TMEM109 Knockout cell line (A549) | Human | TMEM109 | 1:3~1:4 | Negative | Online Inquiry |
TMEM109 Gene Knockout Cell Lines are genetically engineered cell lines designed to specifically disrupt the expression of the TMEM109 gene. This innovative product provides researchers with a powerful tool to investigate the functional roles of TMEM109 in various biological processes. By utilizing CRISPR-Cas9 technology, these cell lines serve as an invaluable resource for studying gene function, cell signaling pathways, and interactions with disease mechanisms.
The primary mechanism by which the TMEM109 Gene Knockout Cell Lines operate is through the complete ablation of TMEM109 expression, leading to phenotypic changes that can be readily monitored in a controlled laboratory environment. Researchers can analyze cellular behaviors, including proliferation, differentiation, and response to external stimuli, thereby elucidating the gene's involvement in critical physiological and pathological processes.
The scientific importance of these knockout cell lines extends into both basic research and clinical applications. For example, understanding the role of TMEM109 in cellular metabolism and stress responses can contribute to novel therapeutic strategies for diseases such as cancer or neurodegenerative disorders. In clinical settings, the insights gained from these studies can inform biomarker development and personalized treatment approaches.
Compared to conventional gene silencing methods, such as RNA interference, TMEM109 Gene Knockout Cell Lines provide a more permanent and stable means of gene manipulation. This permanence allows for robust long-term studies and eliminates the variability often associated with transient knockdown techniques. Additionally, the precise genome editing achieved through CRISPR technology yields highly specific knockout models, reducing off-target effects and ensuring research integrity.
For researchers and clinicians striving to advance their understanding of gene function and its implications in health and disease, TMEM109 Gene Knockout Cell Lines represent a high-value addition to their experimental toolkit. With a commitment to quality and innovation, our company specializes in developing cutting-edge biological products designed to empower discovery and accelerate scientific advancement.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.