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TMEM101 Knockout Cell Lines

Gene: TMEM101

Official Full Name: transmembrane protein 101provided by HGNC

Gene Summary: Involved in positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24912 TMEM101 Knockout cell line (HeLa) Human TMEM101 1:3~1:6 Negative Online Inquiry
KO24913 TMEM101 Knockout cell line (HCT 116) Human TMEM101 1:2~1:4 Negative Online Inquiry
KO24914 TMEM101 Knockout cell line (HEK293) Human TMEM101 1:3~1:6 Negative Online Inquiry
KO24915 TMEM101 Knockout cell line (A549) Human TMEM101 1:3~1:4 Negative Online Inquiry

Background

TMEM101 Gene Knockout Cell Lines are advanced cellular models engineered to facilitate the study of the TMEM101 gene's role in various biological processes. This gene encodes a protein believed to be involved in the regulation of cellular functions, including cellular traffic and signal transduction pathways, which can significantly impact metabolic and developmental processes. By utilizing CRISPR/Cas9 technology, our cell lines offer specific and efficient knockout of the TMEM101 gene, allowing for precise investigation into its functional contributions in different cellular contexts.

The primary mechanism of action for these knockout cell lines involves the introduction of targeted mutations that disrupt the expression of the TMEM101 gene. Researchers can observe the resultant phenotypic changes that occur in the absence of this gene, providing insights into its physiological and pathological roles. These alterations can reveal critical information regarding cellular homeostasis, disease states, and potential therapeutic targets, underscoring the utility of these cell lines in both fundamental and applied biomedical research.

The scientific importance of TMEM101 gene knockout models is underscored by their broad applications in research environments focused on cancer, metabolic syndromes, and neurobiology. By unraveling the functions of TMEM101, researchers can identify novel biomarkers, develop targeted therapies, and enhance our understanding of complex disease mechanisms. Compared to alternative models, our TMEM101 gene knockout cell lines deliver unparalleled specificity, reproducibility, and relevance, reducing the risk of off-target effects found in other genetic manipulation techniques.

For researchers and clinicians aiming to advance their studies of gene function or innovate therapeutic strategies, these cell lines represent a high-value asset. They empower scientific exploration with robust tools to decipher gene roles with clarity and precision. Our commitment to excellence in biological product development, backed by extensive R&D expertise, ensures that TMEM101 Gene Knockout Cell Lines meet the highest standards of reliability and performance in the laboratory setting.

Please note that all services are for research use only. Not intended for any clinical use.

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