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TMED9 Knockout Cell Lines

Gene: TMED9

Official Full Name: transmembrane p24 trafficking protein 9provided by HGNC

Gene Summary: This gene is a member of a family of genes encoding transport proteins located in the endoplasmic reticulum and the Golgi. A similar gene in mouse is the target of microRNA miR-296, which is part of an imprinted cluster. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04031 TMED9 Knockout cell line (HeLa) Human TMED9 1:3~1:6 Negative Online Inquiry
KO04032 TMED9 Knockout cell line (HCT 116) Human TMED9 1:2~1:4 Negative Online Inquiry
KO04033 TMED9 Knockout cell line (HEK293) Human TMED9 1:3~1:6 Negative Online Inquiry
KO04034 TMED9 Knockout cell line (A549) Human TMED9 1:3~1:4 Negative Online Inquiry

Background

TMED9 Gene Knockout Cell Lines are genetically modified cell lines that have been engineered to lack the TMED9 gene, which plays a critical role in mediating intracellular transport and protein sorting within the Golgi apparatus. These knockout cell lines provide invaluable tools for studying the biological functions and molecular pathways associated with TMED9, including its impact on cellular signaling, protein trafficking, and endoplasmic reticulum (ER) stress responses.

The key mechanism of these cell lines revolves around the complete absence of TMED9 protein, allowing researchers to elucidate the physiological and pathological roles of this gene. By analyzing the resulting cellular phenotypes, such as alterations in protein secretion, cellular morphology, and response to stressors, scientists are able to gain insights into TMED9’s involvement in various diseases, including cancer and neurodegenerative disorders. This makes TMED9 knockout cell lines particularly significant for basic research and therapeutic discovery, as they enable the assessment of potential drug targets and molecular interactions that might be modulated in clinical settings.

One of the standout advantages of TMED9 Gene Knockout Cell Lines compared to other models is their specificity and precision in gene editing. Traditional gene knockout techniques can often result in off-target effects or incomplete gene disruption; however, these cell lines utilize advanced CRISPR/Cas9 technology, ensuring a high degree of specificity and efficiency. This precision not only enhances reproducibility in experiments but also reduces the variability that researchers often encounter with less refined models.

The value of TMED9 Gene Knockout Cell Lines to researchers and clinicians cannot be overstated. They represent a powerful resource for both experimental design and validation, facilitating significant advancements in our understanding of cellular functions and disease mechanisms. Institutions engaged in drug development and translational research will find these cell lines instrumental in identifying potential therapeutic interventions and elucidating complex biological processes.

As a pioneer in the field of genetic modifications and biological products, our company brings extensive expertise and a commitment to delivering high-quality, validated research tools. TMED9 Gene Knockout Cell Lines exemplify our dedication to empowering researchers with innovative solutions that advance scientific knowledge and improve clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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