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TMED3 Knockout Cell Lines

Gene: TMED3

Official Full Name: transmembrane p24 trafficking protein 3provided by HGNC

Gene Summary: Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Located in Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29314 TMED3 Knockout cell line (HeLa) Human TMED3 1:3~1:6 Negative Online Inquiry
KO29315 TMED3 Knockout cell line (HCT 116) Human TMED3 1:2~1:4 Negative Online Inquiry
KO29316 TMED3 Knockout cell line (HEK293) Human TMED3 1:3~1:6 Negative Online Inquiry
KO29317 TMED3 Knockout cell line (A549) Human TMED3 1:3~1:4 Negative Online Inquiry

Background

TMED3 Gene Knockout Cell Lines are specialized cellular models engineered to specifically disrupt the TMED3 gene, a crucial component involved in various cellular processes, including protein transport and endoplasmic reticulum function. This gene knockout is achieved through advanced genomic editing techniques, allowing for precise alterations in the cellular DNA that facilitate in-depth studies of gene function and the implications of TMED3 in physiological and pathological states.

The key mechanism of action involves the use of CRISPR-Cas9 technology, which introduces targeted double-strand breaks in the TMED3 locus. Cellular repair processes either fail to mend these breaks properly or incorporate mutations, resulting in a functional knockout of the gene. This precise disruption empowers researchers to explore the downstream effects of TMED3 loss, including impacts on cellular homeostasis, stress response mechanisms, and potential links to diseases such as cancer and neurodegenerative disorders.

From a scientific perspective, TMED3 Gene Knockout Cell Lines serve as essential tools in both academic and clinical research settings. They provide a robust platform for investigating the role of TMED3 in various biological pathways and assessing new therapeutic strategies aimed at modulating these pathways. Their use can facilitate drug discovery processes and preclinical testing, offering insights into how targeting TMED3 may influence cellular behavior.

What sets this product apart from alternatives is its high specificity and reliability in gene disruption. Unlike traditional methods, the CRISPR-based approach ensures precise editing without off-target effects, significantly reducing the experimental variability that often hampers the interpretation of results. Researchers can thus expect more reproducible data, enhancing the validity of their findings.

The value of TMED3 Gene Knockout Cell Lines lies in their ability to streamline research efforts and accelerate the discovery of novel therapeutic interventions. For researchers and clinicians looking to advance their understanding of genetic influences on disease, this product represents an invaluable resource that embodies cutting-edge genomic technology.

Our company is committed to excellence in biotechnology and provides a wide array of genetically engineered cell lines tailored to meet the evolving needs of the scientific community. With years of expertise in developing reliable biological products, we ensure that our TMED3 Gene Knockout Cell Lines uphold the highest standards of quality and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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