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TMC7 Knockout Cell Lines

Gene: TMC7

Official Full Name: transmembrane channel like 7provided by HGNC

Gene Summary: Predicted to enable ion channel inhibitor activity and mechanosensitive monoatomic ion channel activity. Predicted to be involved in sensory perception of mechanical stimulus. Predicted to be located in plasma membrane. Predicted to be active in neuronal cell body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13358 TMC7 Knockout cell line (HeLa) Human TMC7 1:3~1:6 Negative Online Inquiry
KO13359 TMC7 Knockout cell line (HCT 116) Human TMC7 1:2~1:4 Negative Online Inquiry
KO13360 TMC7 Knockout cell line (HEK293) Human TMC7 1:3~1:6 Negative Online Inquiry
KO13361 TMC7 Knockout cell line (A549) Human TMC7 1:3~1:4 Negative Online Inquiry

Background

TMC7 Gene Knockout Cell Lines are advanced cellular models specifically engineered to have the TMC7 gene inactivated. TMC7 (Transmembrane Channel-like 7) is implicated in various physiological processes, including mechanosensation and cellular signaling pathways. These knockout cell lines provide researchers with a powerful tool for studying the gene's function, its role in disease mechanisms, and the potential for therapeutic interventions.

The key mechanism underlying these cell lines is the CRISPR-Cas9 gene-editing technology, which enables precise alterations in the genome. By creating a targeted knockout of the TMC7 gene, researchers can observe the resulting phenotypic changes and cellular behaviors, facilitating a deeper understanding of the molecular pathways that involve TMC7. This allows for the examination of cellular responses to mechanical stimuli, as well as interactions with other cellular components.

The scientific importance of TMC7 Gene Knockout Cell Lines is significant, particularly in the fields of neurobiology and cancer research. They are indispensable for elucidating the role of mechanotransduction in sensory systems, as well as the implications of TMC7 in malignancies. These models are invaluable for investigating potential strategies for drug development and improving therapeutic outcomes.

Compared to other knockout models, TMC7 Gene Knockout Cell Lines offer unique advantages such as higher specificity, reproducibility, and reduced off-target effects. Furthermore, their availability in various cellular backgrounds enhances their applicability across different research disciplines.

In summary, TMC7 Gene Knockout Cell Lines provide crucial insights into the gene's biological significance and its potential role in disease progression. By utilizing these innovative models, researchers and clinicians can advance their studies and contribute to the development of targeted therapies. Our company specializes in cutting-edge genetic engineering and cell line development, ensuring high-quality products that meet the evolving needs of the scientific community and facilitate breakthrough discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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